Which anti-arrhythmic causes the lease decrease in contractility?
amiodarone
When using anti-arrhythmics what parameter must be monitored carefully?
BP - decreasing contractility decreases CO so BP can fall.
How does sympathetic stimulation affect contractility?
neurotransmitters epi and norepi are released and stimulate beta receptors in heart. this increases heart rate and contractility. (dopamine and dobutamine can mimic this)
How does parasympathetic stimulation affect contractility
blocks the beta receptors (eg metoprolol and propranolol) decreasing contractility and decreases heart rate