Opioid Analgesics and Neuroleptanalgesia

Opioid Analgesics (class) tx uses
- analgesia
- constipation
- sedation
- cough suppression
Opioid Analgesics (class) side effects
- resp depression
- constipation
- nausea and vomiting
- sedation/excitation
- intracranial pressure rise
Opioid Analgesics (class) name drugs
- morphine
- heroin (diamorphine)
- codeine
- methadone
- pethidine
- pentazocine- mew antagonist/K agonist
- etorphine
- fentanyl
- remifentanyl
- butorphanol
- buprenorphine- mew partial agonist/k antagonist
- tramadol
- (naloxone)- mew,d,k antagonist
- (diprenorphine)- weak mew partial agonist
morphine

gold standard
codeine

like morphine but weaker analgesic
methadone
- long acting
- orally active
pentazocine
- mew antagonist
- k agonist so makes patient feel sick
etorphine

very potent, good for big animals
buprenorphine
- mew partial agonist
- k antagonist
tramadol
- weak mew agonist
- NA reuptake inhibitor so increases a2 receptor activation
butorphanol

short lasting
naloxone

mew,d,k antagonist, very useful in overdose
diprenorphine
- potent but weak mew partial agonist
- reverses etorphine overdose

Author

rach394

57096

Card Set

Opioid Analgesics and Neuroleptanalgesia

Description

Opioid Analgesics and Neuroleptanalgesia (mew, d , k meant as the greek letters for the 3 opioid receptors)

Updated

2010-12-23T13:29:23Z

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