-
post trauma pain not relieved by medication, limb pale and pulseless (M's of)
compartment syndrome
-
compartment syndrome can lead to what?
tissue ischemia, hypoxia, and necrosis
-
dark reddish brown urine (M's of)
Myoglobinuria a/w rhadbomyolisis
-
what happens when OPG binds to RANK?
deactivation of osteoclasts resulting in bone growth
-
what happens when RANKL binds to RANK?
activation of osteoclasts resulting in bone resorption
-
Rickets can lead to what physical deformities? Why?
damage to growth plates can cause Kyphosis, Genu valgum, or Genu vacuum
-
what bone disorder is a/w deficiency of bile and soft bones?
osteomalacia
-
In what bone disorder is the problem most likely internally caused?
osteoporosis
-
joint pain, vertebral fractures, and muscle weakness (M's of)
osteomalacia
-
in what bone disorder is the damaged caused by a failure in calcification?
osteomalacia
-
sinus, ear, and dental infection can cause ___
osteomyelitis
-
what bone disorder is a/w being bitten, having surgery, or open fractures?
osteomyelitis
-
what lasting affects on infants and children does osteomyelitis have?
infants may have stunted growth, children may suffer improper/deforming bone growth
-
nonspecific symptoms of infection, joint pain, and muscle pain/spasm (M's of)
osteomyelitis
-
what bone disorder can be blamed on a defective B-cell named Iggi?
Multiple myeloma (B-cell makes IgG, IgG makes Il-6, Il-6 causes bone resorption)
-
what bone disorder commonly limits itself to the bones of the central body?
multipel myeloma
-
proteinurea, acure renal failure, recurrent pneumonia, pathologic fractures (M's of)
multiple myeloma
-
multiple myeloma is a/w what protein?
Bence-Jones
-
what disorder's M's are caused by excess fluid and calcium in the muscles?
Duchenne Muscular Dystrophy
-
progressive muscle weakness, enlarged calf muscles, respiratory and cardiac problems (M's of)
Duchenne Muscular Dystrophy
-
what disorder is a/w Lyme disease, trauma, and HIV?
fibromyalgia
-
diffuse burning/gnawing pain, and fatigue (M's of)
fibromyalgia
-
what disorder is a/w soggy, weak cartilage; and osteophytes?
osteoarthritis
-
organize the players: proteolytic and collegenolytic enzymes, cartilage, osteophytes, chrondrocytes, proteoglycan
Chrontrocytes make p & c enzymes - enzymes destroy proteoglycan - cartilage gets weak - osteophytes start growing
-
pain in at least 1 weight bearing joint, stiffness dissipates after a few minutes, nocturnal pain not relieved by rest (M's of)
osteoarthritis
-
ulnar drift and subcutaneous nodules are a/w ___
rheumatoid arthritis
-
morning stiffness lasting over 1 hr, malaise, fatigue, diffuse musculoskeletal pain (M's of)
rheumatoid arthritis
-
muscle or tendon stiffening and shortening, scales, loss of hair (M's of)
systemic lupus erethematosus (SLE)
-
joint pain and inflammation; butterfly rash; heart, lung, renal, and CNS involved too (M's of)
systemic lupus erythematosus (SLE)
-
M's usually found in large joints, may include inflammation of the eye and cervical subluxation (M's of)
juvenile rheumatoid arthritis
-
chronic inflammation of the pigmented layer of the eye, and bone fusion in joints (M's of)
juvenile rheumatoid arthritis
-
abrupt pain in the great toe and kidney stones (M's of)
gout
-
joint pain with nodules that may be white and are periodically red and inflamed (M's of)
gout
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