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Law of segregation
2 alleles for a given gene will separate during meiosis and end up in different gametes
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Law of independent assortment
One pair of alleles segregates independently of another pair of alleles during gamete formation
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linked genes
really close on chromosome, inherited together
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recombinant genes
when crossing over happens, genes recombine
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what is the important experiment that provided evidence for sex-linked genes?
fruit fly experiments by Thomas Hunt Morgan
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Griffith
used S. pneumoniae and mice to show that bacteria can be transformed
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Hershey & Chase
used bacteriophages to show that DNA is genetic material.
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Franklin and Wilkins
X-ray diffraction images of DNA
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Watson & Crick
deduced the structure of DNA was a double helix
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Linnaeus
no evolution; created classification system of taxonomy
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Lamarck
inheritance of acquired traits
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Erasmus Darwin
evolution from a common ancestor; competition and sexual selection responsible for species change
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Malthus
believed that resources can only support a limited population
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Empedocles
natural theory of struggle among species
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Alfred Wallace
proposed same evolutionary theory that Darwin did
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Aristotle
created Scala Natura; believed hierarchy of organisms was fixed
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Hutton & Lyle
Gradualism (changes occur slowly in gradual steps)
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Cuvier
Catastrophism (affected in the past by short-lived, violent events, possibly world-wide)
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5 assumptions of HW
- 1. infinite population
- 2. no gene flow (or migration)
- 3. random mating
- 4. no natural selection
- 5. no mutation
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what 2 forces create genetic variation?
- mutation
- sexual recombination
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what 3 forces alter allele frequencies in a population?
- gene flow
- natural selection
- genetic drift
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what 2 forces preserve genetic variation?
- balancing selection
- diploidy
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what are 4 modes of selection?
- directional
- stabilizing
- disruptive
- sexual
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what are 2 modes of speciation?
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heterochrony
changes in rate and timing of developmental events
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allometry
changes in relative growth rates of different body parts
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homeotic genes
control body plans and the developmental face of cells
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hox genes
determine the position of morphological structures during development
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exaptation
characters that evolved for purposes other than those they are used for
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homoplasy
similarities due to convergent evolution
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outgroup
species least closely related to the rest in a phylogenetic tree
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maximum likelihood
phylogenetic tree based on how DNA changes over time
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orthologous genes
used to compare sequences between species to determine ancestry
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paralogous genes
used to compare sequences within a species to trace evolution of species
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3 threats to biodiversity
- 1. habitat loss
- 2. introduced/invasive species
- 3. overexploitation
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order in which life originated
- 1. abiotic synthesis of small organic molecules
- 2. small molecules joined together into macromolecules
- 3. molecules packed into protobionts
- 4. self-replicating molecules originate
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evolution of prokaryotes, anaerobic bacteria
3.5 bya
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accumulation of oxygen
2.7 bya
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single celled eukaryotes emerge
2.1 bya
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common ancestor of animals
700 mya
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cambrian explosion
530 mya
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animals, plants, fungi colonize land
460 mya
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permian mass extinction
250 mya
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origin of mammals
180 mya
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cretaceous mass extinction
65 mya
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cell wall
maintains cell shape, provides physical protection, prevents cell from bursting
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taxis
movement towards or away from a stimulus
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plasmids
- rings of self-replicating DNA that carry special functions
- 2 types: R (antibiotic resistance) and F (sex)
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transformation
uptake of foreign DNA from surroundings
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transduction
bacteriophages carry bacterial genes from one host cell to another
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conjugation
genetic material is transferred b/w 2 bacterial cells that are temporarily joined
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heterocytes
specialized Anabena cells that carry out nitrogen fixation
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how is HIV different from normal viruses?
- it's a retrovirus
- reverse transcriptase
- can transform RNA to DNA
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model organisms
- nematodes: RNA
- sea urchin: cyclin (the protein regulating cell cycling, cancer)
- jellyfish: GFP
- seashells: pain/addiction
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3 stage approach
- 1. make a linkage map
- 2. make a physical map
- 3. DNA sequencing
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shotgun approach
- 1. cut up a genome into overlapping fragments
- 2. DNA sequencing
- 3. order the sequences
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green algae
archaeplastids
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plasmodial slime molds
mycetozoans
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trypanosoma
kinetoplastids
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4 traits unique to land plants
- 1. alternations of generations
- 2. walled spores produced in sporangium
- 3. multicellular gametangia
- 4. apical meristems
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6 main functions of plasma membrane proteins
- 1. transport
- 2. enzyme activity
- 3. signal transduction
- 4. cell recognition
- 5. intracelular joining
- 6. attachment to other surfaces
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in protostome development, coelom develops from?
mesoderm
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