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Endocrine Glands
- Pituitary
- Thyroid
- Parathyroid
- Pancreas
- Adrenals
- Gonads
- Placenta
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Anterior Pituitary
- Growth Hormone (GH)
- Somatotropin
- Luteinizing Hormone (LH)
- Follicle Stimulating Hormone (FSH)
- Thyrotropin
- Adrenocorticotropic Hormone (ACTH)
- Prolactin
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Bromocriptine
(Parlodel)
- Inhibits anterior pituitary function
- -Dopamine inhibits prolactin
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Thyroid
- *Normal function requires iodine; deficiency causes goiter
- -Hyperthyroidism -Hypothyroidism
- Fight or flight Rest or digest
- Grave's Disease Child=Cretinism
- Plummer's Disease Adult=Myxedema
- Hashimoto's Disease
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Thyroid Treatment
- Thyroid Replacement (Hypo)-
- *Levothyroxine (synthroid)
- *Liotyronine (Cytomel)
- *Liotrix (Thyrolar)
- *Thyroglobulin (Proloid)
- *Desiccated Thyroid
- Antithyroid (Hyper)-
- *Iodine
- *Propylthiouracil (PTU)
- *Methimazole (Tapazole)
- *Radioactive Iodine
- *Partial Thyroidectomy
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Diabetic Cautions
- *Drugs that may increase or decrease insulin and should be used with caution.
- -Epi
- -Glucocorticoids
- -Opioid analgesics
- Okay if diabetes is under control
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Diabetes Treatment
- Type 1-insulin
- Type 2-Diet and exercise, sulfonylureas, biguanides, alph-glucosidase inhibitors, Thiazolidinediones
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Types of Insulin
- Rapid- Novolin R, Humulin R, Semilente
- Intermediate- NPH, Humilin H, Lente
- Long- PZI, Humulin U, Ultralente
- Mixed
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Sulfonylureas
- First line of treatment after diet and exercise
- "Glyburide is the most common"
- Stimulates the release of insulin from pancreas
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Biguanides
- Metformin-used most commonly used even though sulfs are used first
- Inhibits production of glucose from liver
- Main problem is is lactic acidosis
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Alph-Glucosidase Inhibitors
- Acarbose
- Slows down the breakdown of ingested fats
- Slightly less effect than the two already mentioned
- Can be used for both diabetic types
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Thiazolidinediones
- Troglitazone
- Reduces insulin resistance
- Can decrease hematocrit
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Oral Contraceptives
- Higher chance of dry socket
- Higher chance of candida infection
- Decreased glucose tolerance
- Antibiotic interaction
- Can increase blood pressure
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