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MED-Mark 1 Kit
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Functional Class
Atropine: parasympatholytic
Pralidoxime chloride: cholinesterase reactivator
Mechanism of Action
Atropine counters parasympathetic response from muscarinic receptor over-stimulation associated with organophosphate and nerve agent poisoning
Pralidoxime chloride reactivates acetylcholinesterase by binding to it and subsequently releasing the phosphoryl group associated with the poisoning
Indications
Organophosphate and nerve agent poisonings in MCIs
Contraindications
None in emergency setting
Precautions
No prophylactic protection, only administer if s/s present
Do not treat fasiculations caused by nicotinic receptor over-stimulation
Side Effects
Dry mouth
Flushing
Pupil dilation
Tachycardia
Dosage and Route
Contains
:
Atropine 2 mg
Pralidoxime chloride 600 mg
Minor symptoms initially: One Mark 1 Kit autoinjector
If severe symptoms set in within 10 mins of first dose: Two Mark 1 Kits autoinjectors
If severe symptoms present initially:
Three Mark 1 Kits
Note
Tube one (atropine) is always administered first
Diazepam is drug of choice for fasiculations
Author
amerelman
ID
54307
Card Set
MED-Mark 1 Kit
Description
MED-Mark 1 Kit
Updated
2010-12-08T14:46:55Z
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