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Chapter 17 Bio Lecture
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Human Genome Project
the sequencing of genome
bioformatics
a field of science developed to analyze DNA sequences
hierarchical sequencing
a method for genome sequencing
steps
-ID short markers along chromosomes
-pieces cut and sequenced marker to marker
Bacterial artificial chromosome (BAC)
fragments inserted here then that inserted into bacteria
genomic library
a collection of clones containing many different fragments of a genome
Shotgun Sequencing
a method involving directly cutting genomic DNA into smaller, overlapping fragments
high-throughput sequencing
fast cheap ways to sequence and analyze large genomes
functional genomics
the biological discipline that assigns functions to the products of genes
comparative genomics
the comparing of genome sequences from different organisms
transposable elements
segments of DNA sequences that can move from place to place in the genome
transposons
elements that carry additional genes
metagenomics
describes the analyzing genes without isolating the intact organisms
gene families
groups of closely related genes
pseudogenes
nonfunctional genes that arise from mutations (represented by greek letters)
highly repetitive sequences
short sequences that are repeated thousands of times in tandem arrangements in the genome
moderately repetitive sequences
short sequences repeated 10-1000 times in a genome
haplotype
a linked piece of chromosome formed from SNPs
proteome
the total amount of protiens produced by an organism (more complex than its genome)
metabolome
the quantitative description of all the small molecules in a cell or organism
Author
kickenbugg
ID
53858
Card Set
Chapter 17 Bio Lecture
Description
Ch 17 "Genomes"
Updated
2010-12-07T01:52:10Z
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