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Central Nervous system
brain and spinal cord
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brain
- -cerebrum
- -corpus callosum
- -cerebellum
- -limbic system
- -brainstem
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spinal cord
- -emergeges from the skull through the foramen magnum
- -courses through the vertebral foramen of the spinal column
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Peripheral nervous system (PNS)
- -contains nerve fibers that connect the CNS to the muscles and sense organs
- -housed outside of bone
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Somatic Nervous System (SNS)
- -under voluntary control
- -functional systems:
- -pyramidal
- -extrapyramidal
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Pyramidal
- -arises from motor strip
- -conscious initiation of movement
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extrapyramidal
- -arises from pre-motor strip
- -provides muscle tone, background support for movement
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autonomic nervous system (ANS)
- controls autonomic functions (internal organs and glands)
- -subsystems:
- -sympathetic system
- -parasympathetic system
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sympathetic system
- responds to stimulation through energy expenditure
- -"fight or flight"
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parasympathetic system
responsible for quieting the body and conserving energy (undo-ing sympathetic stimulation)
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Cerebrum
- -largest structure of nervous system
- -flat sheet of cells
- -aka "gray matter"
- -white matter connects cerebrum to rest of nervous system
- -divided into right/left hemispheres
- -5 lobes
- -wrapped by 3 meningeal linings
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lobes of cerebrum
- frontal
- parietal
- occipital
- temporal
- insular
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meningeal linings of cerebrum
- dura mater
- arachnoid mater
- pia mater
- -protect brain and hold structures in place
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Dura mater
- -two layers of tough lining mostly attached to the skull
- -most superficial of meninges
- -extends away from skull to line major divisions of cerebrum
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arachnoid mater
- -many blood vessels through this space
- -cerebrospinal fluid flows through this layer
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pia mater
- -thin fascia like covering
- -closely follows the contours of the brain
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falx cerebri
- -seperates 2 hemispheres of the cerebrum
- -mid-sagital division of cerebrum
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falx cerebelli
seperates 2 hemispheres of the cerebellum
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Infoldings of the Dura Mater
- -falx cerebri
- -falx cerebelli
- -tentorium cerebelli
- -diaphragma sella
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tentorium cerebelli
horizontal dural shelf at the base of the skull that divides the cerebral and cerbellar regions
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diaphragma sella
forms an anterior horizontal boundary between teh cerebrum and optic chasm
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cerebrospinal fluid (CSF)
- surronds CNS
- -produced by the choroid plexus within each ventricle
- -flows through 4 ventricles in brain and arachnoid mater
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4 Ventricles
- -Lateral ventricles (paired)
- -3rd ventricle
- -4th ventricle
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lateral ventricle
composed of 4 spaces bounded superiorly by the corpus callosum and extending into each of the lobes of the cerebrum
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3rd Ventricle
located between the left and right thalami and hypothalami
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4th ventricle
- -diamond shaped
- -projects upward from the central canal of the spinal cored and lower medulla
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structure of cerebrum
- -cortex (gray matter)- 6 cell layers
- -divided into 2 halves
- -hemispheres connected by corpus callosum (white matter)
- -divided into 5 lobs
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Cell types of Cerebrum
- -pyramidal cells
- -nonpyramidal cells
- -glial cells
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pyramidal cells
involved in motor function
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nonpyramidal cells
- small and star-shaped
- sensory or intercommunicative in function
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glial cells
- provide nutrition and waste disposal
- provide blood-brain barrier
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6 layers of Cerebrum
- -Molecular- contains glial cells and axons from lower layers & receives input from other cortical areas
- - external granular- contains many small pyramidal cells & receives input from other cortical layers
- -external pyramidal- contains medum sized pyramidal neurons which send outputs to other cortical areas
- -internal granular- receives input from thalamus and other cortical areas
- -internal pyramidal- contains largest pyramidal cells which send output to motor centers beyond the cerebrum
- -multiform- consists of pyramidal cells that send info to the thalamus
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5 lobes of Cerebrum
- frontal
- parietal
- occipital
- temporal
- inular
- (and limbic systme)
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Insula
- deep to frontal, parietal and temporal
- beneath lateral sulcus/fissure
- involved with maintaining the body and with emotion
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limbic system
- deep structures under cerebrum
- integration pts for info to/from cerebrum and cerebellum to brainstem
- basal ganglia-motor
- hippocampus- memory
- thalamus-sensory
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lateral sulcus
divides temporal lobe form the frontal and anterior parietal lobes
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major sulcus
seperates frontal and parietal lobes
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frontal lobe
- -most cognitive functions
- -initiation and inhibition of activity
- -anterior frontal lobe damage can have effects on personality and motivation
- -posterior frontal lobe damage can lead to speech disorders and paralysis/paresis in limbs
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landmarks in frontal lobe
- frontal operculum (brocas area)
- orbital region
- precentral gyrus (motor strip)
- supplementary motor area (SMA)
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frontal operculum (broca's area)
important for speech motor planning
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orbital region
- region overlying eyes
- memory, emotion, motor inhibition, intellect
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precentral gyrus (motor strip)
site of initiation of voluntary motor movement
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supplementary motor area (SMA)
motor strip n SMA give rise to corticospinal tract, that innervates sympathetic nervous system
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motor control
- -things close to each other in the body are close to each other in brain
- -org is contralateral
- -org is inverted
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parietal lobe
- location for somatic (body) sensory reception
- sensory integration from all sensory areas
- -posterior to motor strip
- -anterior/superior to occipital lobe
- -superior to temporal lobe
- contralateral org
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landmarks in parietal lobe
- postcentral gyrus (somatosensory cortex)
- association areas
- supramarginal gyrus and angular gyrus
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postcentral gyrus
- -sensory counterpart to motor strip
- org in same way
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association areas
vision, audition, and somatic sense
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supramarginal gyrus and anular gyrus
involved in reading and writing
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temporal lobe
- site of auditory reception
- key landmarks:
- -heschl's gyrus (area 41)-all auditory info processed here
- -area 42- higher order processing region for auditory stimualtion
- -Wernicke's area (area 22)-damage here results in language damage
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occipital lobe
region responsible for receiving visual stimulation and higher-level visual processing
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insula
- next to subcortex
- basic body maintenance and emotion
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subcortex (limbic system)
- -the part of the pathway between the sensory and motor structures and the cerebrum where info is integrated
- -basal ganlia
- -hippocampus
- -thalamus
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hindbrain
- primitive part of the brain involved in basic autonomic survival functions and in "low-level" details of movement
- -cerebellum
- -brainstem
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basal ganglia
- -paired structure
- -control/coordination of movement and initiation of movement
- -connections to thalamus, motor cortex, and somatosensory cortex
- -substructures:
- -caudate nucleus
- -putamen
- -globus pallidus
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hippocampus
- paired structure
- -implicated in memory function
- -communicated with thalamus and temporal lobe
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thalamus
- -paired structure
- -final, common relay station for sensory info directed toward cerebral cortex
- -all sensation except olfaction passes through it
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cerebellum
- -automatic motor coordinating center
- -controls balance, posture, and synergy of voluntary movement
- -3 lobes: anterior, middle, flocculonodular
- -3 layers of cells: molecular, purkinje, granular
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Anterior lobe of cerebellum
controls muscle tone operating against gravity
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middle lobe of cerebellum
coordinates fine motor adjustments
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flocculonodular lobe of cerebellum
communicates with the vestibular system and coordinates body position in space
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Molecular cell layer and granular cell layer
connect within cerebellum
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purkinje cell layer
project to nucleii and out of cerebellum
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connections of cerebellum
- connects to brainstem through three penducles:
- superiro, middle, and inferior
- -4th ventricle occupies space between the cerebellar peduncles and the brainstem
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brainstem
- -controls basic body functions like heart rate and breathing
- -connects brain to spinal cord
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medulla
- -of brainstem
- -consists of transmission pathways
- -pyramidal tract
- -pyramidal decussation
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pyramidal tract
carries signals to muscles from cortex
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pyramidal decussation
motor commands from one hemisphere cross to serve the opposite side of the body (juncture for contralateral organization
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pons
- -brainstem
- -connects motor planning centers of brain to cerebellum
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midbrain
- -brainstem
- -connecting link between lower and higher brain centers
- -connects cerebellum to cerebrum and basal ganglia
- -relays auditory and visual info
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cerebrovascular system
-vascular supply for the brain arises from two arteries: carotid and vertebral
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carotid artery
- divides cerebrovascular system into the right and left internal carotid arteries
- -L/R internal arteries feed into the circle of Willis
- -provide blood to brain
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vertebral artery
- divied cerebrovascular system into right and left branches, and feeds into the basilar artery in posterior brain
- -L/R arteries combine and become the basilar artery which feed into circle of Willis
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Circle of Willis
- series of junctures between arteries that completely encircles the optic chasm
- -provides redundant pathways for blood flow to regions of cerebral cortex
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Cranial nerve I
goes directly to olfactory areas
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Cranial nerve II-IV
found at the level of the midbrain
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cranial nerve V-VIII
are at the level of the pons
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cranial nerves IX-XII
are found in medulla
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GSA
incoming general sensory info for somatic system
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SSA
incoming special sensory ifo for hearing and vision
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GVA
incoming general sensory info for visceral system
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SVA
incoming special sensory info for taste and smell
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GVE
outgoing autonomic muscle control (for digestion and glands
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GSE
innervation of skeletal musculature
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SVE
innervation of musculature for mastication and deglutition
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cranial nerve I olfactory
- special visceral afferent nerve
- -not a true cranial nerve because it reaches brain w/out passing through thalamus first
- -contains sensory fibers
- -mediate sense of smell
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cranial nerve II
- optic nerve
- -special afferent nerve
- -sensory fibers that merge at the optic chiasm
- -enters brainstem at midbrain
- -processes visual info
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cranial nerve III
- occulomotor
- -contains motor fibers for eye movements(general somatic efferent)
- -serves extrinsic ocular muscles ipsilaterally
- -also for pupil constriction and focus
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cranial nerve IV
- trochlear
- -general somatic efferent
- -contains motor fibers for eye movements
- -innervates superior oblique muscle contralaterally
- -turns eye down and in/out
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cranial nerve VI
- abducens
- -general somatic efferent
- -contains motor fibers for eye movements
- -abductor muscle
- -motor innervation to the lateral rectus ocular muscle
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cranial nerve V
- trigeminal
- -3 major branches (tri-geminal)
- -motor supply to the muscles of matication and tensor veli palatini
- -transmits sensory info form the face
- -general somatic afferent
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cranial nerve VII
- facial
- -contains both sensory and motor fibers
- -supplies muscles of the face and the stapedius in middle ear
- -serves salivary glands
- -provides taste for anterior 2/3 of tongue
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cranial nerve VIII
- vestibulocochlear
- -primarily sensory
- -special somatic afferent
- -carries nerves for hearing and balance
- -efferent portion serves cochlear hair cells that are involved in actively tuning hearing
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cranial nerve IX glossopharyngeal
- contains sensory and motor fibers
- -serves the face, tongue and phayrnx
- -posterior tongue and soft palate taste receptors
- - touch, temp, and pain sense from posterior tongue, faucial pillars, upper pharynx
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cranial nerve IX
- -glossopharyngeal
- -innervation of stylopharyngus and superior pharyngeal constrictor (special visceral efferent)
- -innervation of parotid gland for salivaiton (general visceral efferent)
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cranial nerve X
- -vagus
- "wandering nerve"
- -runs throughout chest and abdomen
- -mix of sensory and motor fibers
- -supplies more visceral structures than any other cranial nerve
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branches of vagus (CN X)
- superior laryngeal nerve
- recurrent laryngeal nerve
- pharyngeal branch
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superior laryngeal nerve
-external branch-innervates cricothryroid muscles for pitch control, special visceral
efferent-internal branch- sensory for the tongue and mucosa of the supralaryngeal area, general visceral afferent
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recurrent laryngeal nerve
- supplies all of the intrinsic laryngeal muscles, except cricothyroid (sve)
- supplies subglottal laryngeal muscosa (GVA)
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pharyngeal branch
- -taste (SVA) and sensation (GVA) from base of tongue and upper pharynx
- -innervation of upper and middle pharyngeal constrictors, plalopharyngeus, lev
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cranial nerve XI
- accessory
- -contains only motor fibers
- -SVE
- -serves muscles of pharynx, soft palate, and neck
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cranial nerve XII
- hypoglossal
- -motor nerve that supplies:
- all intrinsic tongue muscles
- most of extrinsic tongues muscles
- infrahyoid muscles
- -GSE
- -contralateral innervation
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