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antibiotic
having or pertaining to the ability to destroy or interfere with the development of a living organism
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Antiseptic
One of the two types of topical antimicrobial agent; a chemical that inhibits the growth and reproduction of microorganisms without necessarily killing them.
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Bacteriostatic antibiotics
antibiotics that do not actually kill bacteria but rather inhibit their growth
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beta-lactam
the designation for a broad, major class of antibiotics that includes four subclasses: penicillins, cephalosporins, carbapenems, and monobactams; so named b/c of the beta-lactam ring that is part of the chemical structure of all drugs in ths class.
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beta-lactamase
any of a group of enzymes produced by bacteria that catalyze the chemical opening of the crucial beta-lactam ring structures in beta-lactam antibiotics
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beta-lactmase inhibitors
meds combined with certain penicillin drugs to block the effect of beta-lactmase enzymes
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colonization
the establishment and growth of microorganisms on the skin, open wounds, or mucous membranes, or in secretions without causing adverse clinical signs and symptoms
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definitive therapy
the administration of antibiotics based on known results of culture and sensitivity testing identifying the pathogens causing infections
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disinfectant
one of two types of topical antimicrobial agent; a chemical applied to nonliving objects to kill microorganisms. also called cidal agents
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empiric therapy
the administration of antibiotic based on the practitioners judgment of the pathogens most likely to be causing an apparent infection; it involves the presumptive treatment of an infection to avoid treatment delay before specific culture info has been obtained
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glucose-6-phosphate dehydrogenase (G6PD) deficiency
an inherited disorder in which the red blood cels are partially or completely deficient in glucose-6-phosphate dehydrogenase, a critical enzyme in the metabolism of glucose
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prophylactic antibiotic therapy
antibiotics taken before anticipated exposure to an infectious organism in an effort to prevent the development of infections
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pseudomembranous colitis
a necroinflammatory bowel condition that is often associated with antibiotic therapy. a more general term that is also used is antibiotic-associated colitis
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slow acetylation
a common genetic host factor in which the rate of metabolism of vertain drugs is reduced
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subtherapeutic
referring to antibiotic treatment that is ineffective in treatinf a given infection. possible causes include inapropriate drug therapy, insufficient drug dosing, and bacterial drug resistance
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teratogens
substances that can interfere with normal prenatal development and cause one or more developmental abnormalities in the fetus
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sulfonamides
- -sulfamethoxazole combined with trimethoprim commonly used (Bactrim)
- -inhibit the growth of susceptible bacteria by preventing bacterial synthesis of folic acid
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