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Viscerotropic Viral Diseases
- Yellow Fever
- Infectious Mononucleosis
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Viral Gastroenteritis
- Viral Fevers
- Cytomegalovirus Disease
- Acquired Immunodeficiency Disease
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Yellow Fever
- Yellow fever was the first human disease associated with a virus
- Yellow fever virus transmitted by mosquitoes, thus also referred to as an arbovirus(arthropod-borne)
- Can cause jaundice and internal bleeding
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Infectious Mononucleosis
- A blood disease, especially of antibody- producing B-cells Dangerous complications include development of heart defects, paralysis of face, rupture of spleen and liver involvement
- Caused byEpstein-Barr virus - Herpesvirus
- Also causesBurkitt’s lymphoma and chronic fatigue syndrome
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Hepatitis A
- Acute inflammatory disease of the liver
- Most commonly transmitted by food or water contaminated by feces of an individual infected with this virus
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Hepatitis B
- Second major type of hepatitis known as serum hepatitis
- Transmission usually involves direct or indirect contact with an infected body fluid such as blood or semen More severe than hepatitis A
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Hepatitis C
- Liver damage develops slowly and insidiously, such thatcirrhosis is beyond repair by the time the disease is diagnosed
- Most oftentransmitted by drug injection, and sometimes associated with tattoos or body piercing
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Viral Gastroenteritis
- Commonly caused by Rotaviruses
- Severe childhood diarrhea
- Coxsackieviruses also can be causative agents
- Frequentcause of aseptic meningitis
- “24 hour flu”
- Echovirusesalso can be involved
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Viral Fevers
- Some of these are accompanied by severe hemorrhagic lesions
- Lassa fever
- Marburg disease
- Ebola hemorrhagic fever - Ebola virus
- Hantavirus pulmonary syndrome -Hantavirus
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Cytomegalovirus Disease
- Caused by Cytomegalovirus
- May be among the most common diseases in U.S.
- Fever, malaise, enlarged spleen
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Acquired Immunodeficiency Disease
- Caused by Human Immunodeficiency
- Virus Target is CD4T-helper lymphocyte, thus shutting down effective immunity in host
- Transmitted by infected blood or semen
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