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Dermatropic Viral Diseases
- Herpes simplex
- Other Hepesvirus infections
- Chickenpox (Varicella)
- Measles (Rubeola)
- Rubella (German Measles)
- Erythemal Infectiosum
- Mumps
- Smallpox (Variola)
- Molluscum contagiousm
- Warts
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Herpes simplex
- Large viruses Virus passes among cells by intercellular bridges andremains in the nerve cells until something triggers it to multiply
- A number of clinical manifestations:Cold sores
- Herpes encephalitis
- Neonatalherpes
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Gingivostomatitis
series of cold sores in throat: children
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Herpes keratitis
can lead to blindness
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Herpes Two forms
- Type I virus: inhabits areas above waist
- Type II virus: inhabits areas below waist
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Other Hepesvirus infections
- Human herpesvirus 6: possible relationship to multiple sclerosis
- Human herpesvirus 8: cause of Kaposi’s sarcoma
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Chickenpox (Varicella)
- Actually a Herpesvirus
- Highly contagious transmitted by droplet inhalation and skin contact
- Begins in respiratory tract, with fever, headache, then passes into bloodstream and localizes in the peripheral nerves and skin
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Chickenpox (Varicella) pt 2
- Multiplication in the cutaneous tissues results in the generation of fluid-filled vesicles
- Adult disease form ofchickenpox whereby virus multiplies in nerve ganglia causing painful blisteringand other debilitating symptoms
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Reye Syndrome
- serious complication associated with aspirin to control fever
- Herpes-Zoster: known as shingles.
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Measles (Rubeola)
- Highlycontagious virus
- Upper respiratory disease accompanied by fever and characteristic red rash
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Rubella (German Measles)
- Thought to be a mild form of measles, but actuallyindependent clinical entity caused by a Togavirus
- Mild disease: most dangerous to developing fetus
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Erythemal Infectiosum
Caused by a Parvovirus infecting children Characteristic fiery red rash on cheeks and ears
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Mumps
- Characterized by enlarged jaw tissues arising from swollen salivary glands
- Mumps virus transmitted by droplet inhalation, contact and fomites
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Smallpox (Variola)
- First signsare high fever and general weakness,soon followed by tell-tale pink-red spots (macules).
- These become papules, then fluid-filled vesicleswhich develop into deep pustules. Whenpustules break open, they emit infectiouspus, and leave scars or pocks
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Molluscum contagiousm
Disease accompanied by wart-like lesions
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Warts
- Caused by Human Papilloma viruses
- May be associated with cervical cancer
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