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Nerves that lie in the outer regions of the nervous system
- Peripheral Nervous System
- (PNS)
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Originates from the brain
Cranial Nerves
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Originates from the spinal cord
Spinal Nerves
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Consists of all incoming sensory pathways
Afferent Division
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Consists of all outgoing motor pathways
Efferent Division
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Carries information to the somatic effectors (skeletal muscles)
Somatic Motor Division
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Carries feedback information to somatic integration center in the Central Nervous System
Somatic Sensory Division
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Prepares the body to deal with immediate threats to the internal enviroment; produces fight or flight response
Sympathetic Division
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Coordinates the body's normal resting activities; sometime called the "rest and repair" division
Parasympathetic Division
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conduct impulses away from spinal cord or brain toward muscles or glandular tissue
Efferent (motor) Neurons
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conduct impulses to spinal cord or brain
Afferent (sensory) Neurons
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onle one axon and one dendrite; least numerous kind of neuron
Bipolar
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one process comes off neuron cell body but divides almost immediately into two fibers; central fiber and peripheral fiber
Unipolar
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one axon and several dendrites
Multipolar
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Dendrites and cell body are in what functional region of the neurons
Input Zone
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Axon hillock are in what functional region of the neuron
Summation Zone
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axon is in what function region of the neuron
Conduction zone
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telodedria and synaptic knobs of axon are in what function region of the neuron
Output zone
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a single process extending from the axon hillock, sometimes covered by a fatty layer is called a
Myelin Sheath
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swellings that make contact (synapse) with other cells
Axon varicosites
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small knoblike protrusions on dendrites of some brain neurons; serve as connection points for axons of other neurons
Dendritic Spines
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conducts impulses to the CNA from the receptors
Afferent neurons
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conduct impulses from the CNS to effectors (muscle or glandular tissue)
Efferent neurons
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most common; consists of afferent neurons, interneurons, and efferent neurons
Three-neuron arc
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simplest form; consists of afferent and efferent neurons
Two-neuron arc
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nerves with predominatly motor neurons
Motor Nerves
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nerves with predominantly sensory neurons
Sensory Nerves
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in gray matter and referred to as nuclei
- CNS
- (Central Nervous System)
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in gray matter referred to as ganglia
- PNS
- Peripheral Nervous System
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in white matter the myelinated nerves
- PNS
- (Peripheral Nervous System)
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in white matter the myelinated tracts
- CNS
- (Central Nervous System)
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fibrous coat surrounding numerous fascicles and blood vessels to form a complete nerve
Epineurium
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connective tissue holding together fascicles (bundles of fibers)
Perineurium
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delicate layer of fibrous connective tissue surrounding each nerve fiber
Endoneurium
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bundles fo peripheral nerve fibers held together by several layers of connective tissue
Nerves
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when a stimulus triggers the opening of additional K+ channels, increasing the membrane potential (hyperpolarization)
Inhibition
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whena stimulus triggers theopening of additionl na+ channels, allowing the membrane potential to move toward zeoro (depolarization)
Excitation
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slight shift ways formt he resting membrane in a specific region of the plasma membrane
Local potentials
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a membrane that exhibits a membrane potential
Polarized Membrane
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slight excess of positively charged ions on the outside of the membrane and slight deficientcy of positively charged ions on the inside of the membrane
Membrane potential
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the membrane potential of a neuron that is conducting an impulse; also known as a nerve impulse
Action potential
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brief period (0.5ms) during which a local area of a neuron's membrane resists restimulation and will not respond to a stimulus, no matter how strong
Absolute Refractory Period
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time during which the membrane is repolarized and restoring the resting membrane potential; the few milliseconds after the absolute refractory period; will respond only to a very strong stimulus
Relative refractory period
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occurs where cells joined by gap junctions allow an action potential to simply contine along postsynaptic membrane
Electrical Synapses
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occur where presymaptic cells release chemical transmitters (neurotransmitters) across a tiny gap to the postsymaptic cell possible inducing an action potential there
Chemical Symapses
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timy buldge at the end of a terminal branch of a presymaptic neuron's axon that contains vesicles housing neurotransmitters
Symaptic Knob
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space between a symaptic knob and the plasma membrane of a postsymaptic neuron
Symaptic Cleft
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axon signals postsynaptic dendrite; common
Axodendritic
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axon signals postsynaptic soma; common
Axosomatic
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axon signal postsynaptic axon; may regulate action potential of postsynaptic axon
Axoaxonic
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adding together the effects of several knobs being activated simultaneously and stimulating different locations on the postsynaptic membrane producing an action potential
Spatial Summation
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when synaptic knobs stimulate a postsynaptic neuron in rapid succession, their effects can summate over a brief period of time to produce an action potential
Temporal Summation
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stored by facilitating (or inhibiting) synaptic transmission
Memories
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(sec or min) may result from axoaxonic facilitation or inhibition of the presynaptic axon terminal
Short-term Memories
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(min to weeks) happens when serotonin blocks potassium channels in the presynaptic terminal thus prolonging the action potential and increasing the amount of neurotrasmitter released
Intermediate long-term memory
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(month or yrs) requires structural changes at the synapse
Long-term memory
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means by which neurons communicate with one another; more than 30 compounds
Neurotransmitters
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the mechansim by which neurotrasmitters cause a change; function vary by location, they are usually classified according to chemical structure
Chemical Structure
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neuropeptides
Large molecule neurotrasmitter
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(nerve growth) stimulate neuron development but can act as neurotrasmitter
Neurotrophins
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proposes neuron is basic structural and function unit of the nervous system and neurons are independent units connected by chemical synapses
Neuron Doctrine
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proposes nervous system is best unerstood as a large integrated network
Reticular Theory
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act as receptors to detect changes in the internal and external environment; relay information to integrator mechanisms in the CNS
Sensory neurons
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tumors arising in nervous system structure
neuroma
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a common type of brain tumor
glioma
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a type of brain tumor (glioma) that originates from astrocytes
Astrocytoma
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a highly malignant form of astrocytic tumor that spreads throughout the white matter of the brain
Glioblastoma Multiforme
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a glial tumor arising from ependymal cells which line the fluid filled cavities of the brain and spinal cord
Ependymoma
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tumor that commonly occurs in the anterior portion of the brain and has a perak incidence at 40 yrs of age. Would be glioma of oligodendrocytes
Oligodendroglioma
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a lesion of the sheath of Schwann cells surrounding the eighth cranial nerve, responsible for hearing and balance
Acoustic Neuroma
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is an inheritied disease characterized by numerous fibrous neuromas throughout the body
Multiple neurofibromatosis
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the enzyme that inactivates dopamine and serotonin
Monoamine Oxidase (MAO)
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nerve growth factors that are release by various cells of the body
Neurotrophins
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