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Multisystem
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Describe the symptoms/signs of SLE.
Malar/discoid rash
Photosensitivity- exposure to UV light causes a rash
Oral ulcers (including nasopharyngeal ulcers)
Arthritis
Serositis – pericarditis or pleuritis or evidence of a pericardial effusion
Renal disorder – proteinuria > 0.5g/d or 3+ or cellular casts
Neurologic disorder – seizures or psychosis
Haematologic disorder - haemolytic anaemia or leukopenia or lymphopenia or thrombocytopenia
Immunologic disorder – Anti-dsDNA, anti-Sm and/or anti-phospholipid
Antinuclear antibodies - an abnormal titre of ANA
Name 5 drugs that can cause SLE.
Hydralazine
Isoniazid
Methyldopa
Quinidine
Interferon-a
What is rheumatoid factor?
Rheumatoid factors are autoantibodies of the IgG,
IgA or IgM class which react with the Fc portion of IgG
What are the medications for SLE? (name 4)
Prednisone
Rituximab
Cyclophosphamide
Anti-malarials
Author
cathy4xo
ID
50396
Card Set
Multisystem
Description
Multisystem
Updated
2010-11-18T10:26:46Z
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