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Mucosa
- innermost tissue layer
- all nutrients must cross it to enter the blood
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submucosa
layer of connective tissue containing blood vessels, lymph vessels, and nerves.
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muscularis
2 or 3 layers of smooth muscles responsible for mvoement in GI tract
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serosa
- outermost layer of the GI tract wall
- connective tissue that surrounds and protects other layers
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Gastrointestinal tract layers
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Digestive System Processes
1) Mechanical Processing and Movement
chewing, mixing, and propelling
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Digestive System Processes
2) Secretion
fluid, digestive enzymes, hormones, bile, acid, alkali, mucus are secreted into the GI Tract.
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Digestive System Processes
3) Digestion
contents of lumen are broken down into the smallest absorbable units
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Digestive System Processes
4) Absorption
through mucosa into blood or lymph vessels
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Digestive System Processes
5) Elimination
Undigested material is eliminated form the body
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bolus
food chewed into a mass
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peristalsis
- propels food down the GI tract by wave like muscle contractions
- mainly in esophagus
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segmentation
- mixes food by muscles contracting and relaxing
- mainly in small intestine
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The mouth
- begins digestion
- -teeth
- - tongue
- - saliva
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swallowing
- delivers food to stomach
- voluntary phase: tongue pushes bolus of food into pharynx
- involuntary phase: receptors in pharynx stimulated by presence of food
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epiglottis
closes opening to trachea
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pharynx
- common passage way for air, liquid, and food
- participates in swallowing
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esophagus
- connects pharynx to stomach
- mix of smooth and skeletal muscles
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hiatal hernia
when the stomach protrudes through the diaphragm
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stomach
- food storage
- digestion
- regulates food flow
- does not absorb nutrients
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How long does it take to empty stomach?
2-6 hours
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small intestine
- digestion: adds enzymes and bile
- breaksdown carbohydrates, protiens and lipids
- 95% of absorption happens here
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How long is the small intestine?
about 11 feet
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duodenum
area of most digestion
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mucosa adaptations to the small intestine
folds covered with villi and microvilli give more surface area
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villi of small intestie
contain blood and lacteal capillaries, which take in small water soluble nutrients and lipids, respectivly.
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pancreas
secretes digestive enzymes and sodium bicarbonate
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liver
produces bile and emulsifies fats
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hepatic protal system
carries nutirent rich blood from the digestive tract for processing (in liver)
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gallbladder
- stores bile
- secretions are sent to the duodenum
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How long is the large intestine?
5 feet
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Large intestine
- absorbs some nutrients and water
- eliminates waste
- NO digestion
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feces
indigestible material, bacteria
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defecation reflex
due to stretch as feces enter the rectum
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diarrhea
- often due to bacteria infection
- too little water is absorbed
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constipation
waste remains too long in th large intestine causeing too much water to be absorbed
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lactose intolerance
- difficulty in digesting lactose in milk products
- Doug
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diverticulosis
- mucosa sacs protrude through layers of the large intestine
- may become inflamed or infected
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polyps
- non cancerous growth from colon mucosa
- ususally removed because they can become cancerous over time, ie. colon cancer
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hepatitis
- inflammation of the liver
- Mom's friend
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gallstones
too much cholesterol in bile
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peptic ulcers
open sores in the stomach or small intestine
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crohn's disease
- inflammatory disorder that damages the intestinal lining
- Lauren
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irritable bowel syndrome
- abdominal pain, diarrhea, constipation
- effects smooth muscle's ability to move feces through colon
- Becky
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anorexia
- excessive dieting and exercise leads to lower weight than the ideal
- Paris Hilton
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bulimia
- binge and purge
- damage teeth, rupture stomach
- Lindsy Lohan
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urinary system
regulates: water levels, nitrogenous and other solute waste
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kidneys
principle organ; filters blood to produce urine
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renal cortex
outside layer of the kidney
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renal medulla
pyramid shaped muscles; inner layer of kidney
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renal pelvis
where urin collects after it is formed
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ureters
transprot urine to the bladder by peristalsis
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urinary bladder
stores urine
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how much urine can the bladder hold?
600-1000mL
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urethra
carries urine from body; two sphincters
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nephrons
- funcitonal unit that produces urine
- 1 million per kidney
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tubules
filter fluid and reabsorb needed substances
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bowman's / glomerular capsule
surrounds a network of capillaries
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glomerulus
blood supply of the nephron; contained inside bowman's capsule
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glomerular filtration
- based on pressure difference
- filters water, and small solutes into glomerular capsule
- filtrate is formed
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tubular reabsorption
returns most of the water and needed solutes back to the blood
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tubular secretion proximal tubules
removes other substances form blood back to tubules
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Purpose of tubular secretion in proximal tubules
- regulation of chemical levels in body
- excretion of harmful chemicals
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what is secreted?
- penicillin
- cocaine
- mary jane
- pesticides
- preservatives
- H ions
- ammonium
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dilute urine
excreting excess water when Anti-diuretic hormone is absent and reabsorption of salt without reabsorption of water
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concentrated urine
conserving water due to increased anti-diuretic hormone
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micturition reflex
as bladder fills, stretching occurs, and sphincters come into play
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kidney stones
- minerals in urine crystallize in renal pelvis
- can be surgically removed or crushed with ultrasonic shock waves
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Urinary Tract Infection
presence of microbes in urine or an infection in any part of the urinary system
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acute and chronic renal failure
conditions that impair kidney functions temporarily
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scrotum
sac, regulates temperature of testes
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testes
produce sperm and testosterone
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penis
- conveys urine and sperm
- erectile tissue; functions in sexual intercourse
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seminal vesicles
secretes fructose, seminal fluid
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prostate gland
secretes watery alkaline fluid; neutralizes acidic vagina
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bulbourethral gland
- secretes lubricating mucus
- cleanses urethra
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ovaries
- release eggs
- secrete estrogen and progesterone
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eggs are also known as...
an oocytes
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oviduct is also known as
- fallopian tube
- uterine tube
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fallopian tube
- fringed ends to receive egg
- is not connected to ovary
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uterus
the hallow, pear-shaped organ where fertilized egg grows and develops
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endometrium
- innermost layer of uterus
- site where fertilized egg implants
- sloughs off during menstrual flow
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myometrium
- smooth muscle
- expands during pregnancy
- constricts during labor
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cervix
- opening to the uterus
- permits sperm to enter the uterus
- allows the fetus to exit during birth
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vagina
- organ of sexual intercourse
- birth canal
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external genitalia
vulva including labia majora and labia minora
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clitoris
female erectile tissue
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Breasts include
- mammary gland
- 100s of milk producing lobules; ducts; adipose tissue
- lactation
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mammary glands
undergo changes due to hormones at puberty, during and after pregnancy
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lactation
milk production, estrogen and progesterone influence
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How is Sperm made?
in seminiferous tubules it undergoes cell division by mitosis and meosis
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Sperm have how many chromosomes
- 23 (N)
- half than normal cells
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sequence of sperm development
- Spermatogonia 2N
- primary spermatocyte 2N
- secondary spermatocyte N
- sermatids N
- sperm N
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sperm
- head containing DNA
- acrosome with enzymes (tip of head)
- tail with mitochondria
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sperm travel
- to epididymis
- to vas (ductus) deferens
- ejaculatory duct
- urethra
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Testosterone
- made by interstitial/Leydig cells between seminiferous tubules
- controls growth and function of male reproductive tissues
- stimulates aggression, sexual behavior and secondary sexual characteristics
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GnRH, LH & FSH hormones
involved in production and secretion of testosterone
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Menstrual Cycle
- every 28 days
- under hormone control
- begins at puberty
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what two cycles are involved with the menstrual cycle
- ovarian cycle
- uterine cycle
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how many primary oocytes is a female born with?
about 1 million, which are stored in the ovary
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how many eggs are left come time for puberty for a woman?
only 300,000 (most are absorbed)
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What happens each month to primary oocytes?
- several begin development
- usually only 1 completes this process
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Ovarian Cycle
- Immature follicle of 1 oocyte develops, FSH and LH increase
- zona pellucida around oocyte
- antrum space develops, some estrogen and progesterone secreted
- 2 oocyte and polar body produced, follicle matures
- increased estrogen causes surge of LH, ovulation occurs--> follicle ruptures to realse 2 oocyte
- corpus luteum formed from follicle
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