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Powders DF2
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Powders and granules definition
Powders- mixture of finely divided drugs
Granules- powder mixes plus excipients
Bulk powders are ___dose whereas divided powerders are ____ dose.
Multi
Single
Divided forms of oral powders can be
Powder packets
sachet
extampenous powder papers
Powders serve as the starting point for most _____ ____.
Dosage forms
Advantages of oral powders/granules
Stability
convenient to convert to liquid
Convenient for high dose
Disadvantages of oral powders
Requires an added step
Potential misunderstanding on how to take
inaccuracies
Particle size is important for _____ rate, particle flow, and Particle ______ in suspension.
Dissolution rate
Particle settling
Particle flow can affect many variables including
Mixing and pouring
speed of processing
stratification
T/F factors determining particle flow are electostatic charge, absorbed moisture, density, size, shape, and fat content.
True
False
False, fat content is not a factor
eutectic mixture is an alloy which ______ the melting point.
Reduces below room temperature
This mortar and pestle is best for comminuition
Wedgwood
Glazed porcelain mortar and pestle are best for
blending
Levigation definition
Wet grinding, powder is mixed with levigation agent then grinded by either spatulation or trituration.
When blending powders, ________ mixing is ESSENTIAL!!!
Homogeneous
Geometric dilutuion definition
successive equal volume additions of diluent to a concentrate through mixing between each addition.
Effervescent powders are combined with ___/____ mixtures that liberates ___ when combined with water.
Acid/base
CO2
Effervescence aids in ____ _____.
Taste masking
Author
swynocker
ID
49633
Card Set
Powders DF2
Description
Powders DF2
Updated
2010-11-15T04:44:23Z
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