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Emulsions Definition
Two immsicble liquids mixed, one is droplets inside the other.
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T/F o/w emulsions are used for topical creams.
False, W/O emulsions are used for those.
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advantages of oral emulsions
- increased palatability
- improve digestibility
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disadvantages of emulsions
- microbe growth
- heavy
- instability vs solids
- limited use
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T/F industrially the oil/water mixutre is homogenized
True
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T/F droplet aggregation irreversibly alters an emulsion
False, can be reversible.
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Interfacial tension is the force per ____ existing at the _____ between two ______ liquids.
- unit length
- interfact
- Imiscible
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Creaming results from the ______ and concentration of the ______ phase.
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Difference between creaming and coalescence
In coalescence they come together, in creaming they havent come together yet.
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Surfactant emulsifers reduce the ______ needed to mix the immiscible liquids
Force
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Surfactant types
- Electric repulsion (ionic)
- Steric repulsion (non ionic)
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Suspending agents alter the ____ phase.
Continuous
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T/F gums are suspending agents
True
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T/F methyl paraben is oil soluble and propyl, butyl paraben are water soluble.
False, flipped
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HLB means
Hydroliphophilic Balance
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Increased surfactant polarity means increased hydrophilicity True or false?
True
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High HLB will yield a __ emulsion, low HLB will yield a __ emulsion.
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T/F As internal phase volume increases, viscosity decreases.
False, it increases due to increased friction.
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Phase inversions occur when
Internal phase becomes too high (60-85%) and it switches phases.
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Microemulsions are nearly ___________ stable and form _______.
- Thermodynamically
- Spontaneously
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T/F microemulsions are transparent
True, they are smaller than light wave lengths
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Neoral self emulsifies in-____
Vivo
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