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Antibody
protective protein produced by B lymphocytes in response to presence of a foreign substance called an antigen
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Antigen
substance recognized as harmful to the host and stimulates formation of antibodies in an immunocompetent individual
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Bile Pigments
Substances derived from the breakdown of hemoglobin, produced by the liver and excreted in the form of bile
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Cytokines
Chemical substances produced by certain cells that initiate, inhibit, increase or decrease activity in other cells
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Extracellular Fluid
All body fluids found outside cells, including interstitial fluid, plasma, lymph and cerebrospinal fluid
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Host
Organism that maintains or harbors another organism
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Immunocompetent
ability to develop an immune response, or the ability to recognize antigens and respond to them
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Natural Killer Cells
Specialized lymphocytes that kill abnormal cells by releasing chemicals that destroy the cell membrane causing its intercellular fluids to leak out
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Erythrocytes
red blood cells
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Leukocytes
white blood cells
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anisocytosis
condition of marked variation in the size of erythrocytes when observed on a blood smear
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ascites
accumulation of serous fluid in the peritoneal or pleural cavity
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bacteremia
presence of viable bacteria circulating in the bloodstream usually transient in nature
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graft rejection
destruction of a transplanted organ or tissue by the recipient's immune system
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hemoglobin (Hgb) value
measurement of the amount of hemoglobin found in a whole blood
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hematocrit (Hct)
measurement of the percentage of RBCs in a whole blood sample
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Monospot
non specific rapid serological test for infectious mononucleosis; also called the heterophile antibody test
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partial thromboplastin time (PTT)
test that emasures the length of time it takes blood to clot. It screens for deficiencies of some clotting factors and monitors the effectiveness of anticoagulant (heparin) therapy; also called activated partial thromoplastin time (APTT)
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prothrombin time (PT)
test that measure the time it takes for the plasma portion of blood to clot. It is used to evaluate protions of the coagulation system; also called pro time
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red blood cell (RBC) indices
mathematical calculation of the size, volume and concentration of hemoglobin for an RBC
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Schilling test
test used to assess the absorption of radioactive vitamin B12 by the digestive system
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lymphadenography
radiographic examination of lymph nodes after injection of a contrast medium
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lymphangiography
radiographic examination of lymph vessels or tissues after injection of contrast medium
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aspiration
drawing in or out by suction
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bone marrow aspiration
procedure using a syringe with a thin aspirating needle inserted (usually in the pelvic bone) to withdraw a small sample of bone marrow fluid for microscopic evaluation
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biopsy
Representative tissue sample removed from a body site for microscopic examination, usually to establish a diagnosis
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bone marrow biopsy
removal of a small core sample of tissue from bone marrow for examination under a microscope and possibly for analysis using other tests
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sentinel node biopsy
removal of the first lymph node (the sentinel node) that receives drainage from cancer-containing areas and the one most likely to contain malignant cells
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lymphangiectomy
romoval of a lymph vessel
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transfusion
infusion of blood or blood components into the bloodstream
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autologous transfusion
transfusion prepared from the recipients own blood
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homologous transfusion
transfusion prepared from another individual whose blood is compatible with that of the recipient
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transplantation
grafting of living tissue from its normal position to another site or from one person to another
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autologous bone marrow transplantation
harvesting, freezing (cryopreserving) and reinfusing the patients own bone marrow to treat bone marrow hypoplasia following cancer therapy
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homologous bone marrow transplantation
transplantation of bone marrow from one individual to another to treat aplastic anemia, leukemia, and immunodeficiency disorders
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Anticoagulants
prevent blood clot formation by inhibiting the synthesis or inactivating one or more clotting factors
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Sample an an anticoagulants
- 1. TRADE: heparin
- 1. heparin sodium
- 2. TRADE: warfarin
- 2. Coumadin
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antifibrinolytics
neutralize fibrinolytic chemicals in the mucous membranes of the mouth, nose and urinary tract to prevent the breakdown of blood clots
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Sample of an antifibrinolytic
- 1. TRADE: aminocaprioc acid
- 1. Amicar
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antimicrobials
destroy bacteria, fungi and protozoa depending on the particular drug, generally by interfering with the functions of theri cell membrane of their reproductive cycle
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samples of antimicrobials
- 1. TRADE: trimethoprim; sulfamethoxazole
- 1. Bactrim; Septra
- 2. TRADE: pentamidine
- 2. NebuPent; Pentam-300
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antivirals
- prevent replication of viruses within host cells
- used in the treatment of HIV infection and AIDS
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samples of antivirals
- 1. TRADE: nelfinavir
- 1. Viracept
- 2. TRADE: lamivudine/ zidovudine
- 2. Combivir
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