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The
Multiple Endocrine Neoplasias
All are autosomal dominant
pheochromocytomas of MEN-2A and -2B are associated with
ret
protooncogene mutation
MEN-1
(Wermer's Syndrome)
(3ps)
parathyroid tumors (GH, prolactin)
pancreatic endocrine tumors
-Zollinger-Ellison Syndrome
---insulinomas
---vip'omas
---glucagonomas (rare)
MEN-2A
(Sipple's Syndrome)
(2p's)
Medullary Thyroid Carcinoma (secretes calcitonin)
pheochromocytoma
parathyroid tumors
MEN-2B
(1 p)
Medullary thyroid carcinoma (secretes calcitonin)
Mucosal Neuroma's (oral/intestinal ganglioneuromatosis - associated with marfanoid habitus)
pheochromocytoma
Author
SerratYasargil
ID
49165
Card Set
MENs
Description
The Multiple Endocrine Neoplasias
Updated
2010-11-12T21:48:37Z
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