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Hormone produced by G cells in antrum
Gastrin
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Stimulants of gastrin secretion (6)
Amino acids, vagal input(Ach), calcium, ETOH, antral distension, pH>3.0
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Inhibitors of gastrin secretion (6)
pH<3.0, somatostatin, secretin, CCK, VIP, gastric inhibitory peptide
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cells affected by gastrin (2)
parietal cells, chief cells
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effects of gastrin secretion (3)
HCl release, intrinsic factor release, pepsinogen secretion
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Hormone produced by D cells in antrum
Somatostatin
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Stimulants of somatostatin secretion (1)
Acid in duodenum
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Effects of somatostatin secretion
Inhibition of gastrin, HCl, insulin, glucagon, secretin, GIP, motilin, neurotensin, enteroglucagon, decreased pancreatic fistula output
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Hormone produced by K cells in duodenum
Gastric inhibitory peptide
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Stimulants of gastric inhibitory peptide secretion (4)
Amino acids, glucose, long-chain fatty acids, dec pH
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Cells affected by GIP
Parietal cells of stomach, beta cells of pancreas
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Effects of GIP secretion (3)
Decreased HCl and pepsin, increased insulin release
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Hormone produced by I cells of duodenum and jejunum
CCK
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Stimulants of CCK production (2)
Amino acids, fatty acid chains
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Effects of CCK secretion (4)
GB contraction, sphincter of Oddi relaxation, pancreatic enzyme secretion, increased intestinal motility
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Hormone produced by S cells of duodenum
S cells
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Stimulants of secretin secretion (3)
Fat, bile, pH<4.0
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Inhibitors of secretin secretion (2)
pH>4.0, gastrin
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effects of secretin stimulation
pancreatic HCO3 release, inc bile flow, inhibition of gastrin and HCl release
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hormone produced by cells in gut and pancreas
vasoactive intestinal peptide (VIP)
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stimulants of VIP secretion (2)
fat, Ach
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effects of VIP secretion (3)
increased intestinal secretion of water and electrolytes, increased motility, inhibition of gastrin
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hormone released by beta cells of pancreas
insulin
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stimulants of insulin secretion (3)
glucose, glucagons, CCK
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inhibitors of insulin secretion (2)
somatostatin, pancreatostatin
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effects of insulin (2)
cellular glucose uptake, protein synthesis
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hormone released by alpha cells of the pancreas
glucagon
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stimulants of glucagon secretion (4)
dec glucose, inc amino acids, inc Ach, inc gastrin-releasing peptide
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inhibitors of glucagon secretion
high glucose, high insulin, somatostatin
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effects of glucagon (2 main categories, 10 total)
(getting glucose back into circulation) glycogenolysis, gluconeogenesis, lipolysis, ketogenesis, (decreased GI motility) dec gastric acid secretion, dec pancreatic secretion, dec intestinal motility, dec stomach motility, inc LES pressure, dec MMCs
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hormone secreted by islet cells in pancreas
pancreatic polypeptide
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stimulants of pancreatic polypeptide (2)
food, vagal stimulation
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effect of pancreatic polypeptide (2)
decreased pancreatic and GB secretion
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hormone secreted by intestinal cells of gut
motilin
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stimulants of motilin secretion (4)
duodenal acid, food, vagal input, gastrin-releasing peptide
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inhibitors of motilin (4)
somatostatin, secretin, pancreatic polypeptide, duodenal fat
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effect of motilin
increased motility
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receptor that erythromycin acts upon to cause increase in gut motility
motilin
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effect of bombesin (aka gastrin releasing peptide)
increased intestinal motor activity, increase pancreatic enzyme secretion, increase gastric acid secretion
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hormone released from terminal ileum following a fatty meal
Peptide YY
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Effect of peptide YY
Inhibition of acid secretion and stomach contraction, inhibitor of GB contraction and pancreatic secretion
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Recovery time of small bowel postop
24 hours
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recovery time of stomach postop
48 hours
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recovery time of colon
3-5 days
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