Biochem lecture 32

Transport of ammonia to the liver is mostly in the form of _____ or ______.

_____ ______ is responsible for te synthesis of glutamine from glutamate and NH3

glutamate is synthesized by the _____ amination of __________ catalyzed by glutamate dehydrogenase.

Glutamate arises from __________ reactions with the amino nitrogen being donated by a number of different _____ _____.

Glutamine is produced from glutamate by the direct incorporation of _______; which can be considered a ____ _____ reaction.

Role of glutamine is to carry ammonia from ______ _____ to the ____ where it is converted to ammonia by ________.

Second mechanism of ammonia transport is by

pyruvate is transaminated to form _____

Synthesis of urea requires 5 enzymes

Carbomoyl phosphate is the ______ and is inside the ______.

arginine is an allosteric _____

There are _#_ ATPs used in the urea cycle.

OTC is for the formation of

Oxaloacetate fates

Amino group of amino acids are transferred to ________, forming an alpha-keto acid and glutamate via ______.

Glutamate is deaminated to form _______ and to regenerate _____ via glutamine dehydrogenase.

Conversion and elimination of ammonia as _____ via ______ _____ _________ and the urea cycle enzymes.

Metabolism of the carbon backbone occurs via the