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largest artery in the body
aorta
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largest type of blood vessel; carries blood away from the heart to all parts of the body ("a"-"away")
artery
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specialized muscle fibers connecting the atria with the ventricles and transmitting electrical impulses between them
atrioventricular bundle (bundle of His)
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specialized tissue in the wall between the atria
atrioventricular node (AV node)
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one of two upper chambers of the heart
atrium (pl: atria)
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smallest blood vessel
capillary
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gas (waste) released by body cells, transported via veins to the heart, and then to the lungs for exhalation
carbon dioxide (CO2)
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blood vessels that branch from the aorta and carry oxygen-rich blood to the heart muscle
coronary arteries
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blood that is oxygen-poor
deoxygenated blood
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relaxation phase of the heartbeat
diastole
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record of the electricitowing through the heart; represented by waves or deflections called P, QRS, or T
electrocardiogram
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inner lining of the heart
endocardium
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innermost lining of blood vessels
endothelium
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valve between the left atrium and the left ventricle; bicuspid valve
mitral valve
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abnormal swishing sound caused by improper closure of the heart valves
murmur
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muscular, middle later of the heart
myocardium
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heart rhythm originating in the sinoatrial node with a resting rate of 60 to 100 beats per minute
normal sinus rhythm
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gas that enters the blood through the lungs and travels to the heart to be pumped via arteries to all body cells
oxygen
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specialized nervous tissue in the right atrium that begins the heartbeat
pacemaker (sinoatrial node)
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double-layered membrane surrounding the heart
pericardium
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artery carrying oxygen-poor blood from the heart to the lungs
pulmonary artery
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flow of blood from the heart to the lungs and back to the heart
pulmonary circulation
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valve positioned between the right ventricle and the pulmonary artery
pulmonary valve
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one of two pairs of vessels carrying oxygenated blood from the lungs to the left atrium of the heart
pulmonary vein
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beat of the heart as felt through the walls of the arteries
pulse
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partition or wall dividing a cavity; such as between the right and left atria and right and left ventricles
septum (pl: septa)
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pacemaker of the heart
sinoatrial node (SA node)
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instrument to measure blood pressure
sphygmomanometer
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flow of blood from body tissue to the heart and then from teh eheart back to body tissues
systemic circulation
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contraction phase of the heartbeat
systole
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located between the right atrium and right ventricle; it has three leaflets, or cusps
tricuspid valve
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structure in veins or in the heart that temporarily closes an opening so that blood flows in only one direction
valve
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thin-walled vessel that carries blood from body tissues and lungs back to the heart
vein
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largest vein in the body
vena cava (pl: venae cavae)
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one of two lower chamber of the heart
ventricle
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ather/o
yellowish plaque, fatty substance
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cholesterol/o
cholesterol
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abnormal heart rhythms (dysrhythmias)
arrhythmias
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failure of proper conduction of impulses from the SA node through the AV node to the atrioventricular bundle (bundle of His)
bradycardia and heart block (atrioventricular block)
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rapid but regular contractions, usually of the atria
flutter
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very rapid, random, inefficient, and irregular contractions of the heart (350+ bpm)
fibrillation
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abnormalities in the heart at birth
congenital heart disease
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CHD: narrowing (coarctation) of the aorta
coarctation of the aorta (CoA)
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CHD: passageway (ductus arteriosus) between the aorta and the pulmonary artery remains open (patent) after birth
patent ductus arteriosus (PDA)
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small holes in the wall between the atria (atrial septal defects) or the ventricles (ventricular septal defects)
septal defects
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CHD: congenital malformation involving four distinct heart defects
tetralogy of Fallot
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4 defects of tetralogy of Fallot
- pulmonary atery stenosis
- ventricular septal defect
- shift of the aorta to the right
- hypertrophy of the right ventricle
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heart is unable to pump its required amout of blood
congestive heart failure (CHF)
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disease of the arteries surrounding the heart
coronary artery disease (CAD)
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inflammation of the inner lining of the heart
endocarditis
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high blood pressure affecting the heart
hypertensive heart disease
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improper closure of the mitral valve
mitral valve prolapse (MVP)
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extra heart sound, heard between normal beats
murmur
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inflammation of the membrane (pericardium) surrounding the heart
pericarditis
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heart disease caused by rheumatic fever
rheumatic heart disease
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local widening (dilation) of an arterial wall
aneurysm
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blood clot (thrombus) forms in a large vein, usually in a lower limb
deep vein thrombosis (DVT)
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high blood pressure
hypertension (HTN)
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blockage of arteries carrying blood to the legs, arms, kidneys, and other organs
peripheral arterial disease (PAD)
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recurrent episodes of pallor and cyanosis primarily in fingers and toes
Raynaud disease
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abnormally swollen and twisted veins, usually occurring in the legs
varicose veins
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unstable angina and myocardial infarction (heart attack), which are consequences of plaque rupture in coronary arteries
acute coronary syndromes (ACSs)
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chest pain reulting from myocardial ischemia
angina (pectoris)
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antihypertensive drug that blocks the conversion of angiotensis I to angiotensis II causing blood vessels to dilate; prevents heart attacks, CHF, stroke, and death
angiotensis-converting enzyme (ACE) inhibitor
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listening for sounds in blood vessels or other body structures, typically using a stethoscope
auscultation
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drug used to treat angina, hypertension, and arrhythmias; block the action of epinephrine (adrenaline) at receptor sites on cells, slowing the heartbeat and reducing the workload on the heart
beta-blocker
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device enabling ventricles to beat together (in synchrony) so that more blood is pumped out of the heart
biventricular pacemaker
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abnormal blowing or swishing sound heard during auscultation of an artery or organ
bruit
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drug used to treat angina and hypertension; dilates blood vessels by blocking the influx of calcium into muscle cells lining vessels
clacium channel blocker
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sudden, unexpected stoppage of heart action; sudden cardiac death
cardiac arrest
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pressure of the heart caused by fluid in the pericardial space
cardiac tamponade
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pain, tension, and weakness in a leg after walking has begun, but absence of pain at rest
claudication
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drug that treats arrhythmias and strengthens the heartbeat
digoxin
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clot of other substance that travels to a distant location and suddenly blocks a blood vessel
embolus (pl: emboli)
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area of dead tissue
infarction
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drugs used in the treatment of angina; dilate blood vessels, increasing blood flow and oxygen to myocardial tissue
nitrates
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nitrate drug used in the treatment of angina
nitroglycerin
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closure of a blood vessel due to blockage
occlusion
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uncomfortable sensations in the chest related to cardiac arrhythmias, such as premature ventricular contrations (PVCs)
palpitations
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scraping or grating noise heard on auscultation of the heart
pericardial friction rub
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small, pinpoint hemorrhages
petechiae
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drugs used to lower cholesterol in the bloodstream
statins
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vibration felt over an area of turmoil in blood flow (as a blocked artery)
thrill
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clumps of platelets, clotting proteins, microorganisms, and red blood cells on diseased heart valves
vegetations
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measurement of BNP (brain natriuretic peptide) in blood
BNP test
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chemicals are measured in the blood as evidence of a heart attack
cardiac biomarkers
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measurement of cholesterol and triglycerides (fats) in a blood sample
lipid tests (lipid profile)
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lipoproteins (combinations of fat and protein) are physically separated and measured in a blood sample
lipoprotein electrophoresis
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x-ray imaging of blood vessels after injection of contrast material
angiography
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3D x-ray images of the heart and coronary arteries using a CT (64-slice CT scanner)
computed tomography angiography (CTA)
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video equipment and a computer produce x-ray images of blood vessels
digital subtraction angiography (DSA)
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electron beams and CT identify calcium deposits in and around coronary arteries to diagnose early CAD
electron beam computed tomography (EBCT or EBT)
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sound waves measure blood flow within blood vessels
Doppler ultrasound studies
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echoes generated by high-frequency sound waves produce images of the heart
echocardiography (ECHO)
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images show blood flow and myocardial function following uptake of radioactive glucose
positron emission tomorgraphy (PET) scan
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technetium Tc 99m sestamibi injected intravenously is taken up in cardiac tissue, where it is detected by scanning
technetium Tc 99m sestamibi scan
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concentration of radioactive thallium is measured to give information about blood supply to the heart muscle
thallium 201 scan
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images of the heart are produced using radiowave energy in a magnetic field
cardiac MRI
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thin, flexible tube is guided into the heart via a vein or an artery
cardiac catheterization
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recording of electricity flowing through the heart
electrocardiography (ECG)
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an ECG device is worn during a 24-hour period to detect cardiac arrhythmias
Holter monitoring
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exercise tolerance test (ETT) determines the heart's response to physical exertion (stress)
stress test
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brief delivery of radiofrequency or cryosurgery to destroy areas of heart tissue that may be causing arrhythmias
catheter ablation
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arteries and veins are anastomosed to coronary arteries to detour around blockages
coronary artery bypass grafting (CABG)
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brief discharges of electricity are applied across the chest to stop dysrhythmias (ventricular fibrillation)
defibrillation
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surgical removal of plaque from the inner layer of an artery
endarterectomy
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heart-lung machine diverts blood from the heart and lungs while the heart is repaired
extracorporeal circulation
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a donor heart is transferred to a recipient
heart transplantation
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balloon-tipped catheter is inserted into a coronary artery to open the artery; stents are put in place
percutaneous coronary intervention (PCI)
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drugs to dissolve clots are injected into the bloodstream of patients with coronary thrombosis
thrombolytic therapy
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