Pathophys Exam 2

5 most common IDs
- Bacteria
- Viruses
- Prions
- Fungi
- Parasites
Endogenous source

from host's own microbial flora
Exogenous source
- most common
- comes from some other source
Fomite

inanimate object carrying an ID
nosocomial

aquired in the hospital
8th leading cause of death

influenza and pneumonia
10th cause of death

septicemia
6 Pathophysiological steps of ID
- 1. microbial encounter and entry into the host.
- 2. microbial growth after entry
- 3. avoidance of innate host defenses.
- 4. tissue invasion and topism
- 5. tissue damage
- 6. transmission to a new host
Adhesins
- anchor pathogen to host's cells
- may lead to immune response
Tissue tropism

describes the cells and tissues of a host which support the growth of a particular microbe
virulence factors

enhance ability to cause disease
Examples of virulence factors
- toxins
- adhesion factors
- evasive factors
- invasive factors
Normal WBC

4500 to 10,000
nonspecific indicators of inflammation
- erythrocyte sedimentation rate
- c-reactive protein
MIC
- minimal inhibitory concentration
- lowest antimicrobial concentration that prevents visible growth after 24 hours of incubation
3 categories o fdrugs for bacteria
- affect bacterial cell wall
- affect protein synthesis
- affect DNA synthysis

Author

Rx2013

46285

Card Set

Pathophys Exam 2

Description

Infectious Diseases

Updated

2010-10-31T18:14:50Z

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