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Fluoroquinolones exert their bacterial effect by
interfering with the synthesis of bacterial DNA. prevents cell reproduction, leading to death of the bacteria.
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Uses are
lower respiratory infections, bone and joint infections, UTI, infections of the skin and STD's
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Common Adverse effects are
nausea, diarrhea, headache, abdominal pain or discomfort, dizziness and photosensitivity.
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Photosensitivity is
exaggerated sunburn reaction when the skin in exposed to sunlight or ultraviolet light.
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Linezolid (Zyvox) is the first drug in a new drug class,
acts by binding to a site on a specific ribosomal RNA and preventing formation of a component necessary for the bacteria to replicate.
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Vancomycin-Resistant Enterococcus faecium (VREF) is
bacteria resistant to drug vancomycin. common acquired pneumonias and skin and skin structure infections.
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Phenylketonuria is
a genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine, without treatment the disorder results in mental retardation.
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Extended release is
drugs that are release over time in the body.
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Red Man syndrome or red neck is
severe adverse drug reaction characterized by a sudden and profound fall in BP, fever, chills, paresthesias, and erythema (redness) of the neck and back.
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Extravasation is
leakage into the soft tissue.
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Quinupristrin/Dalfopristin is a
bacteriostatic agent used in treatment of VREF.
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