1. Fluoroquinolones exert their bacterial effect by
    interfering with the synthesis of bacterial DNA. prevents cell reproduction, leading to death of the bacteria.
  2. Uses are
    lower respiratory infections, bone and joint infections, UTI, infections of the skin and STD's
  3. Common Adverse effects are
    nausea, diarrhea, headache, abdominal pain or discomfort, dizziness and photosensitivity.
  4. Photosensitivity is
    exaggerated sunburn reaction when the skin in exposed to sunlight or ultraviolet light.
  5. Linezolid (Zyvox) is the first drug in a new drug class,
    acts by binding to a site on a specific ribosomal RNA and preventing formation of a component necessary for the bacteria to replicate.
  6. Vancomycin-Resistant Enterococcus faecium (VREF) is
    bacteria resistant to drug vancomycin. common acquired pneumonias and skin and skin structure infections.
  7. Phenylketonuria is
    a genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine, without treatment the disorder results in mental retardation.
  8. Extended release is
    drugs that are release over time in the body.
  9. Red Man syndrome or red neck is
    severe adverse drug reaction characterized by a sudden and profound fall in BP, fever, chills, paresthesias, and erythema (redness) of the neck and back.
  10. Extravasation is
    leakage into the soft tissue.
  11. Quinupristrin/Dalfopristin is a
    bacteriostatic agent used in treatment of VREF.
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