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Dosage forms test1 stability 2
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Efflorescence
Release of water of hydration from crystal hydrate
Particles clumping is due to
Cohesive properties
Deliquescence
Dissolution of solid upon uptake of atmospheric moisture.
T/F Drugs are chemically more stable in liquid state.
True
False
FALSE- Solid
Uptake of water by solid drug accelerate chemical degradation
Aspirin
Stressing the solid with high humidity tests for
Hygroscopicity
Drugs with high vapor pressure may volatize thru or in container
flavorants, cosolvents, nitroglycerin (can pass out of container)
Author
swynocker
ID
45364
Card Set
Dosage forms test1 stability 2
Description
Stability2
Updated
2010-10-27T05:43:11Z
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