Dosage forms test1 stability 2

Efflorescence

Release of water of hydration from crystal hydrate
Particles clumping is due to

Cohesive properties
Deliquescence

Dissolution of solid upon uptake of atmospheric moisture.
T/F Drugs are chemically more stable in liquid state.

FALSE- Solid
Uptake of water by solid drug accelerate chemical degradation

Aspirin
Stressing the solid with high humidity tests for

Hygroscopicity
Drugs with high vapor pressure may volatize thru or in container

flavorants, cosolvents, nitroglycerin (can pass out of container)

Author

swynocker

45364

Card Set

Dosage forms test1 stability 2

Description

Stability2

Updated

2010-10-27T05:43:11Z