KING TRIAL

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WHERE WAS THE KING STUDY PUBLISHED AND WHEN

2009 DIABETES OBES METABOLISM
WHAT WAS THE STUDY DESIGN OF THE KING STUDY?

RANDOMIZED, DOUBLE BLIND, CROSSOVER
PRIMARY OBJECTIVE OF THE KING STUDY?

TO EVALUTATE IF LEVEMIR AND INSULIN GLARGINE USED ONCE A DAY YIELD SIMILAR 24HR GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES USING CGSM.
HOW MANY PATIENTS WERE IN THE KING STUDY?

36 PATIENTS
WHEN WERE THE PATIENTS GIVEN THE INSULIN INJECTION IN THE KING STUDY?

QD INJECTION AT 8PM EITHER LEVEMIR OR GLARGINE
WHEN WERE THE INSULIN DOSE SWITHCED TO THE OTHER INSULIN IN THE KING STUDY?

AFTER PATIENT ACHIEVED 2 CONSECUTIVE DAYS AT GOAL, THEY WERE SWITCHED AND PROCESS WAS REPEATED.
WHAT WAS THE PRIMARY END POINT IN THE KING STUDY?

COMPARISION OF THE MEAN GLUCOSE VALUES ACHIEVED DURING THE BASAL PERIOD (12AM TO 6AM) BETWEEN LEVEMIR AND GLARGINE.
EXCLUSION CRITERIA FROM THE KING STUDY

PRIOR TREATMENT WITH BOLUS INSULIN
WHEN WAS THE LAST MEAL IN THE KING STUDY FOR PATIENTS?

6PM
AVERAGE AGE IN THE KING STUDY AND BMI?

58.9 YEARS AND 34.9 BMI
HOW MANY DAY DID IT TAKE IN THE LEVEMIR ARM IN THE KING STUDY TO REACH GLYCEMIC CONTROL AND GLARGINE ARM?

LEVEMIR ARM 3.8 DAYS

GLARGINE ARM 3.5 DAYS
WHAT WAS THE MEAN DOSE OF INSULIN IN BOTH ARMS IN THE KING STUDY?

26.3 UNITS LEVEMIR

26.6 UNITS FOR GLARGINE

Author

Susanslcm

45217

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KING TRIAL

Description

ONCE DAILY INSULIN DETEMIR IS COMPARABLE TO ONCE DAILY INSULIN GLARGINE IN PROVIDING GLYCAEMIC CONTROL OVER 24HRS IN PATIENTS WITH TYPE 2 DIABETES: A DOUBLE-BLIND, RANDOMIZED, CROSSOVER STUDY.

Updated

2010-10-26T22:08:22Z