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Chemical equation for cellular respiration
 + energy
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Explain why cellular respiration is an axample of a redox reaction.
- -carbon being oxidized
- - electrons are in sugar molecule are spending alot of time around carbon ( electrons closer to C than H b/c of electronnegativity )
- - Oxidation: when H is shifted away from the part oc in CO2
- - Oxygen becomes part of O in H2O, electrons in covalent bond shifts towads the O ( reduction )
- - no electrons being transferred, only shifting
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Define Substrate level phosphorylation.
- type of chemical reaction that results in the formation and creation of adenosine triphosphate (ATP) or guanosine triphosphate (GTP)
- - adding phosphate
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Define Oxidative phosphorylation.
is a metabolic pathway that uses energy released by the oxidation of nutrients to produce adenosine triphosphate (ATP)
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Name the 2 coenzymes involved in oxidative phosphorylation.
what are thier functions?
NADH : coenzyme found in all living cells
FADH: organic molecule, non protein, vitamins
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What is the role of the electron transport chain in oxidatative phosphorylations?
- carries electron from one protein to another
- - loses energy in the process, the loss energy is used to produce ATP
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Explain why FADH2 produces only 2 ATP while NADH produces 3 ATP.
- it has to do with where the electrons are dropped off
- - NADH drops off at a higher energy level ( 3ATP)
- - FAHD2 drops off at a lower energy level (2ATP)
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explain why oxygen is the "final acceptor" of the electrons in oxidative phosphorylations.
b/c oxygen has the highest electronegativity
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how is most of the ATP in cellular respiration formed?
in the oxidative phosphorylation
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What is Glycolysis?
is the partial "breakdown" of "sugar" into pyruvate to generate ATP.
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Why is glycolysis the most ancient metabolic pathway?
in prokaryates billions of years ago, no oxygen required, in cytosol
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Glucose priming stage.
- when 2 ATP molecules are used to phosphorylate a glucose molecule
- to make it ready; activate it for chemical reactions
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Glucose Splitting stage.
when the phosphorylated sugar is split to form two 3 carbon molecules called Glyceraldehyde phosphate.
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ATP generation stage.
converts the two Glyveraldehyde phosphates into two 3 carbon Pyruate molecules
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How many ATP are formed in glycolysis in the absence and presence of oxygen?
Absence: 4ATP ( substrate level phosphorylation ) - 2ATP ( used in priming stage ) = 2ATP
Presence: 2NADH *(times) 3ATP/NADH = 6+2 = 8 ATP
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How is Acetyl-CoA formed?
The acetyl group combines with coenzyme A (CoA) to form acetyl-CoA
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How is the acetyl groups formed?
one of 3 carbons of the pyruvate is oxidized to form Co2 and a two-carbon molecule
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wht is the function of coenzyme A?
" shuttle bus " to carry out the 2 carbon( acetyl group ) to the next stage( citric acid cycle )
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How many ATP are formed by each sugar molecule during acetyl-CoA formation in the presence of oxygen?
2NADH *(times) 3ATP/NADH = 6 ATP
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Where does the citric acid cycle take place in eukaryotes and prokaryotes?
Eukarytoes: in matrix of mitochondria
Prokaryotes: in cytosol
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How does the citric acid cycle work?
- Combines the 2 carbon acetyl group with a four carbon molecule ( called oxaloacetate) to form a six carbon " citrate" molecule
- - A series of ractions reforms the oxaloacetate, and completely oxidizes the acetyl group into two carbon dioxide molecules.
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How many ATP are formed by each sugar molecule in the citric acid cycle in the presence of oxygen?
- ( 3NADH *(times) 3ATP/NADH) = 9
- (1FADH2 *(times) 2ATP/FADH) = 2
- (1ATP/substrate level phos. ) = 1
- = 12 *(TIMES) 2 = 24 ATP / glucose molecule
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explain how the electron transport chain forms ATP by oxidative phosphorylation.
- when it loses all energy, final acceptor = oxygen -> most electronegative.
- ATP made using hydrogen ion concentration difference
- the teritary structure is changing
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Prokaryotes lack mitchondia. Where does oxidative phosphorylation occur in prokaryotes?
in the plasma membrane
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Define Anaerabic respiration. Explain how some prokaryotes carry out respiration.
- - electron chain is not shut off
- - use sulphate instead SO4 = final acceptor
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How many ATP are formed by each sugar molecule by substrate level phosphorylation?
2ATP for Glycolysis and 2 for citric acid
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How many ATP are formed by each sugar molecule by oxidative phosphorylation?
- Glycolysis= 2NADH times 3ATP/NADH = 6ATP
- Acetyl CoA= 2NADH times 3ATP/NADH= 18ATP
- Citric acid cycle= 6NADH times 3ATP/NADH = 18ATP
- 2FADH2 times 2ATP/FADH2
- = 34 ATP
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how efficient is cellular respiration?
- very efficent 40% of energy of sugar molecule
- - 38 ATP of oxidative phos. and sustrate level phos.
- - 60% went to generating heat
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How are fats broken down in cellular respiration.
- Fatty acids break off leaving 3 carbon backbone
- -> goes into glycolysis
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how are proteins broken down in cellular respiration.
- directly through kidneys
- they are deaminated which = NH4 ( ammonia ) is then converted to urea or detoxified in liver
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what is fermentation?
the partial breakdown of glucose in the absence of oxygen
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Where does fermentation take place?
in cytosol of cell; outside mitochondria
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How many ATP are formed by each glucose molecule using fermentation?
substrate level phosphorylation - 2ATP
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what happens to the electrons of the NADH formed during glycolysis?
recycled vitamins in cytosol
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what is alcohol fermenation?
- occurs in yeast, and involves the oxidization of one of the carbons of pyruvate to form CO2,
- and the reduction of the remaining 2 carbon molecule using NADH to form ethanol
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what are some commerical uses for end products of alcohol fermentation?
-bread, ethanol - waste material of yeast, wie, champagne bottles
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what is lactic acid fermentation?
occurs in fungi and bacteria, and involves the reduction of pyruvate directly using NADH to form ethanol.
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what are some commerical uses for lactic acid?
yogurt
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explain how muscle cramps occur.
- decrease the pH of muscle cells, denaturate the proteins ( actin, myosin )
- - cause by lack of oxygen to muscle- mitochondria shuts off
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