-Vasomotor center – collection of neurons that specialize in activating vascular smooth muscle, which are innervated by sympathetic nerves
3 Types of Capillaries
Continuous
Discontinuous
Fenestrated
Capillaries Continuous
Muscles
Lungs
Fat
Capillaries Discontinuous
Liver
Bone
Spleen
Capillaries Fenestrated
Kidneys
Intestines
Transcapillary exchange: Pinocytosis
means cell drinking. Pieces of the plasmalemma pinches off and captures substances. Relatively large lipid-insoluble material
Transcapillary exchange:
Diffusion
primary way stuff is moved across the capillary. Function of chemical gradient
Transcapillary exchange: Filtration/absorption
movement of plasma or water and whatever is dissolved or suspended in that substance (movement of fluid from outside to inside the capillary)
Factors Affecting Capillary Diffusion
Concentration gradient (high concentration to lower concentration)
Surface area
Permeability
Primary Factors Affecting Coronary Blood Flow
Aortic pressure
Myocyte metabolismExtrava
scular compression
Neural and neurohumoral factors
Viscosity of blood
Hypoxemia
reduced oxygen in systemic arterial blood
Hypoxia
reduced oxygen in tissues
Anoxia
complete lack of oxygen
Myocardial hibernation
significant coronary occlusion where the metabolism slows down in an attempt to preserve itself (reversible)
Coronary stealing
effect of nitrates on coronary blood flow – vasodilating coronary arteries (and veins) to such an extent that you dilate all the other arteries thereby reducing blood flow – reduces preload and afterload which reduces the work done by the heart