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Infection
Invasion of the body by a microorganism.
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Pathogen
An organism that causes disease.
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Lymphatic System
A system of vessels and organs that picks up excess fluid, proteins, lipids, and other substances from the tissues; filters out pathogen and other waste products; and returns the cleansed fluid to the general circulation.
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Systemic Infection
An infection spread by the blood or lympatic system to large portions of the body.
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Neutrophil
Atype of white blood cell that engulfs foreign organisms and infected, damaged, or aged cells; particularly prevalent during the inflammatory response.
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Macrophage
A large phagocytic (cell-eating) cell that devours foreign particles.
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Natural killer cell
A type of white blood cell that directly destroys virus-infected cells and cancer cells.
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Dendritic cells
A white blood cells specialized to activate T and B cells
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Lymphocyte
A white blood cell continuously made in lymphoid tissues as weel as in bone marrow.
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T cell
A lymphocyte that arises in bone marrow and matures in the thymus(thus its name)
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B cell
A lymphocyte that matures in the bone marrow and produces antibodies.
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Helper T cell
A lymphocyte that helps activate other T cells and may help B cells produce antibodies.
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Killer T cell
A lymphocyte that kills body cells that have been invaded by foreign organisms.
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Suppressor T cell
A lymphoctye that inhibits the growth of other lymphocyte.
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Antibody
A specialized protein, by white blood cells, that can recognize and neutralize specific microbes.
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Memory T and B cells
Lymphocytes generated during an initial infection that circulate in the body for years, "remembering" the specific antigens that caused the infection and quickly destroying them if they appear agina.
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Autoimmune Disease
A disease in which the immune system attacks the person's own body.
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Antigen
A marker on the surface of a foreign substance that immune system cells recognize as nonself and that triggers the immune response
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Histamine
A chemical responsible for the dilation and increased permeability of blood vessels in allergic reactions.
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Immunity
Mechanisms that defend the body against infection; specific defenses against specifuc pathogens.
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Incubation
The period of when bacteria or viruses are actively multiplying inside the body's cells; usually a period without symptoms of illness.
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Prodromal Period
The stage of an infection following incubation, during which initial symptoms begin to appear but the host does not feel ill; a highly contagioud period.
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Vaccine
A preparation of killed or weakened microorganisms, inactivated toxins or components of microorganisms that is administered to stimulate an immune response; a vaccine protects against the future infetion by the pathogen.
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Allergy
A disorder caused by the body's exaggerated response to foreign chemcials and proteins; also called hypersensitivty.
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Allergen
A substance that triggers an allergic reaction.
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Anaphylaxis
A severe systemic hypersensitive reaction to an allergen characterized by difficulty breathing, low blood pressure heart arrhythmia, seizure, and sometimes death.
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Bacterium
A microscopic single-celled organism; about 100 bacterial species can cause disease in humans
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Pneumonia
Inflammation of the lungs, typically caused by infection or exposure to chemical toxins or irritants
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Meningitis
Infection of the membranes covering the brain and spinal cord(meninges)
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Streptococcus
Any of a genus of spherical bacteria; can cause skin infections, rheumatic fever pneumonia and toxic shock syndrome.
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Toxic Shock syndrome
Sudden onset of fever, aches, vomiting, and peeling rash folled in some cases by shock and inflammation of multiple organs
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Tuberculosis
A chronic bacterial infection that usually affects the lungs.
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Endemic
Persisten and relatively widespread in a given population
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Virus
A very small infectious agent composed of necleic acid surrounded by a protein coat; lacks and independent metabolism and reproduces only within a host cell.
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Contagious disease
A disease that can be transmitted from one person to another; most are vital diseases such as the common cold or flu
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Influenza
Infection of the respiratory tract by the influenza virus, which is highly infectious and adaptable; the form changes so easily that every year new strains arise, making treatment difficult, commly known as the flu.
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Epidemic
The occurence in a particular community or region of more than the expected number of cases of a particular disease
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Pandemic
A disease epidemic that is unusually severe or widespread; often used to refer to worldwide epidemics affecting a large proportion of the population.
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Herpesvirus
A family of viruses responsible for cold sores, monoucleosis, and chicken pox; frequently causes latent infections.
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Hepatitis
Inflammation of the liver, which can be caused by infection, drugs, or toxins.
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Fungus
A single-celled or multicelled organism that absorbs food from living or dead organic matter
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Protozoan
A microscopic single-celled organism that often produces recurrent, cyclical attacks of disease.
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Parasitic Worm
A pathogen that causes intestinal and other infections
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Prion
Proteinaceous infectious particles thought to be responsible for a class of neurodegenerative diseases
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Sexually Transmitted Disease
A disease that can be transmitted by sexual contact
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Accquired immunodeficiency syndrome
A generally fatal, incurable, sexually transmitted viral disease
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Human immunodeficiency virus
The virus that causes HIV infection and AIDS
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HIV infection
A chronic, progressive viral infection that damages the immune system.
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CD4 T cell
A type of white blood cell that helps coordinate the activity of the immune system; the primary target for HIV infection. A decrease in the number of these cells correlates with the risk and severity of HIV-related illness.
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Hemophilia
A hereditarty blood disease in which blood fails to clot and abnormal bleeding occurs, requiring transfussions of blood products with a specific factor to aid coagulation.
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HIV RNA assay
A test used to determin the amount of HIV in the blood.
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HIV antibody test
A blood test to determine whether a person has been infected by HIV; becomes positive within weeks or months of exposure.
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EUSA(Enzyme-linked immunosorbent assay)
A blood test that detects the presence of antibodies to HIV
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Western blot
A blood test that detects the presence of HIV antibodies; a more accurate and more expensive test used to confirm positive results from an ELISA test.
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HIV positive
A diagnosis resulting from the presence of HIV in the bloodstream; also referred to as seropositive
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Seroconversion
The appearance of antibodies to HIV in the blood of an infected person; usuallt occurs 1-6 months after infections.
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Chlamydia
An STD transmitted by the pathogenic bacterium
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Gonorrhea
A sexually transmitted bacterial infection that usually affects mucous membranes
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Pelvic inflammatory disease
An infection that progresses from the vagine and cervix to the uterus, oviducts, and pelvic cavity
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Human Papilomavirus
The pathogen that causes human wartss including genital warts.
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Genital Warts
A sexually transmitted viral infection characterized by growths on the genitals
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Genital Herpes
A sexually transmitted infection caused by the herpes simplex virus.
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Syphilis
A sexually transmitted bacterial infection caused by the spirochete Treponema pallidum.
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Chancre
The sore produced by syphilis in its earliest stage.
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