-
Labetalol (2)
- Trandate or Normodyne
- B1 Antagonist
- B2 antagonist
- Probably a1 antagonist
- Various cardio diseases
-
Carvedilol
- Coreg
- B1 antagonist
- B2 antagonist
- Possibly a1 antagonist
- Various cardio diseases
-
Nebivolol
- Bystolic
- B1 antagonist
- NO release
- Varios cardio diseases
-
Nebivolol
- Bystolic
- Selective B1 blocker
- Varios cardio disease
- Prophylactic migraine aid
-
Esmolol
- Brevibloc
- Selective B1 blocker
- Various cardio disease
- Prophylactic migraine aid
-
Bisoprolol
- Zebeta
- Selective B1 blocker
- Varios cardio disease
- Prophylactic migraine aid
-
Betaxalol
- Kerlone
- Selective B1 blocker
- Various cardio disease
- Prophylactic migraine aid
-
Acebutolol (syllabus says Avebutolol but it's a typo)
- Sectral
- Selective B1 blocker
- Varios cardio disease
- Prophylactic migraine aid
-
Metoprolol tartrate
- Lopressor
- Selective B1 blocker
- Various cardio disease
- Prophylactic migraine aid
-
Metoprolol succinate
- Toprol xl
- Selective B1 blocker
- Sustained release
- Various cardio disease
- Prophylactic migraine aid
-
Metapranolol
- Optipranolol
- Nonselective B1,B2 blocker
- Glaucoma
-
Levobunolol
- Betagan
- Nonselective B1,B2 blocker
- Glaucoma
-
Carteolol
- Ocupress
- Nonselective B1,B2 blocker
- Glaucoma
-
Penbutolol
- Levatol
- Nonselective B1,B2 blocker
- Varios cardio
- Migraine (propylactic)
-
Pindolol
- Visken
- Nonselective B1,B2 blocker
- Various cardio
- Migraine(prophylactic)
-
Nadolol
- Corgard
- Nonselective B1,B2 blocker
- Various cardio
- Migraine(prophylactic)
-
Propranolol
- Inderal
- Nonselective B1,B2 blocker
- Various cardio
- Migraine(prophylactic)
-
-
Alfuzosin
- Uroxatral
- A1 blocker
- BPH
- HTN
-
-
-
-
-
Phentolamine
- Regitine
- Nonselective A1,A2 blocker
- HTN
-
Dopamine
- Intropin
- Mixed acting agonist
- D1 at low Ro,D1+B1 at medium Ro,D1+B1+A1 at high Ro, plus indirect effects
- Increase force of heart contraction
-
Ephedra
- Ephedrine
- Mixed acting agonist
- A1,A2,B1,B2 plus indirect
- Energy, weight loss
- Decongestant
-
Sudafed
- Pseudoephedrine
- Indirect A1 agonist (also a weak direct agonist)
- Nasal decongestant
-
Brimonidine
- Alphagen P
- Selective direct acting A2 agonist
- HTN
- Glaucoma
-
Apraclonidine
- Iopidine
- Selective direct A2 agonist
- HTN
- Glaucoma
-
Guanfacine
- Tenex
- Selective direct A2 agonist
- HTN
- Glaucoma
-
Guanabenz
- Wytensin
- Selective direct A2 agonist
- HTN
- Glaucoma
-
A-Methyldopa
- Aldomet
- Combines with L-Dopa in Dopa Decarboxylase rxn to eventually become alpha-methyl-NE(in place of normal NE), which will act as a direct A2 agonist
- HTN
- Glaucoma
-
Clonidine
- Catapres
- Selective direct A2 agonist
- HTN
- Glaucoma
-
A-methytyrosine aka
Metyrosine
- Demser
- Inhibits tyrosine hydroxylase to lower sns response
- Treatment of pheochromocytoma
-
A-methyldopa
- Aldomet
- False transmitter, but more so an A2 agonist
- Lowers bp
- HTN
-
Reserpine
- Serpasil
- Inhibits V-MAT 2 presynaptic storage
-
Cocaine and SSRIs
NET inhibitors
-
Guanethidine
- Ismelin
- Kicks NE out of presynaptic storage vesicle to be hydrolyzed by MAO, lowering NE supply
-
Guanadrel
- Hylorel
- Kicks NE out of presynaptic vesicle to be hydrolyzed by MAO, lowering NE supply
-
-
Edrophonium
- Tensilon
- Competitive anticholinesterase
- Diagnosis of myasthenic crisis or cholinergic crisis
- Acts within 30 seconds and ends in minutes
-
Tacrine
- Cognex
- Competitive Anticholinesterase
-
Donepezil
- Aricept
- Competitive anticholinesterase
- Alzheimers dementia
-
Physostigmine
- Eserine and Antilirium
- Substrate inhibitor anticholinesterase
- Glaucoma
- Alzeimers
- Myasthenias gravis
-
Pyridostigmine
- Regonol and Mestinon
- Substrate inhibitor anticholinesterase
- Alzheimers
- Myasthenias gravis
-
Rivastigmine
- Exelon
- Substrate inhibitor anticholinesterase
- Alzheimers
- Prolongs effects of depolarizing NM blockers since ACHe is too occupied to degrade succinylcholine (which it would normally make quick work of)
-
Galantamine
- Razadyne and Reminyl
- Substrate inhibitor anticholinesterase
-
-
-
Selegiline
- Eldepryl and EMSAM
- Selective MAOI (B)
-
-
-
-
Dorzolamide
- Trusopt
- Carbonic anhydrase inhibitor
- Glaucoma treatment by lowering aqueous humor production
-
Brinzolamide
- Azopt
- Carbonic anhydrase inhibitor
- Treats glaucoma by lowering aqueous humor production
-
Latanaprost
- Xalatan
- Prostaglandin analog
- Glaucoma
- Increase Uveoscleral Outflow
-
Travoprost
- Travatan
- Prostaglandin analogs
- Glaucoma
- Increase Uveoscleral Outflow
-
Bimatoprost
- Lumigan
- Prostaglandin analog
- Glaucoma
- Increase Uveoscleral Outflow
-
Pilocarpine (4 brand names)
- Salagen, Pilocar, isoptocarpine, ocusert pilo 20
- M3 agonist contact lense
- Glaucoma
-
Atropine (eye exams)
- M3 blocker
- Induce mydriasis and cycloplegia
-
Homatropine
- M3 blocker
- Causes mydriasis and cycloplegia for eye exams
-
Tropicamide
- Mydriacyl
- M3 blocker
- Used to induce mydriasis and cycloplegia for eye exams
-
Tropicamide and hydroxyamphetamine
- Paremyd
- Tropicamide is an M3 blocker
- Hydroxyamphetamine enters presynaptic vesicle to push NE into synapse indirectly causing sympathetic response
- Induces mydriasis and cycloplegia for eye exams
-
Cyclopentolate
- Cyclogyl
- M3 blocker
- Induces mydriasis and cycloplegia for eye exams
-
Scopolamine
- Transderm Scop
- M3 blocker
- For motion sickness
-
Ipratropium
- Atrovent
- M3 blocker
- COPD
- Asthma
-
Tiotropium
- Spiriva
- M3 blocker
- COPD
- Asthma
-
Benztropine
- Cogentin
- M3 blocker
- Parkinsons adjunct
- Extrapyramidal disorders
-
Trihexyphenidyl
- Artane
- M3 blocker
- Parkinsons adjunct
- Extrapyramidal disorders
-
Tolterodine
- Detrol
- M3 blocker
- Treats overactive bladder
-
Oxybutynin
- Ditropan
- M3 blocker
- Treats overactive bladder
-
Darifenacin
- Enablex
- M3 blocker
- Treatment of overactive bladder
-
Solifenacin
- Vesicare
- M3 blocker
- Treatment of overactive bladder
-
Trospium
- Sanctura
- M3 blocker
- Treatment of overactive bladder
-
Fesoterodine
- Toviaz
- M3 blocker
- Treatment of overactive bladder
-
Flavoxate
- Urispas
- M3 blocker
- Treatment of overactive bladder
-
Propantheline
- Probanthine
- M3 blocker
- GI disorders
- Presurgery
-
Dicyclomine
- Bentyl
- M3 blocker
- GI disorders
- Preop
-
Glycopyrrolate
- Robinul
- M3 blocker
- GI disorders
- Preop
-
Oxymetazoline
- Afrin
- Direct selective A1 agonist
- Vasoconstrictor
- Decongestant
-
Phenylephrine
- Neosynephrine
- Direct selective a1 agonist
- Vasoconstrictor
- Decongestant
-
Formoterol
- Foradil (part of symbicort)
- Direct selective B2 agonist
- Bronchospasm prevention
-
Salmeterol
- Serevent
- Direct selective B2 agonist
- Bronchospasm prevention
-
Albuterol
- Ventolin or Proventil
- Direct selective B2 agonist
- Bronchospasm prevention
-
Terbutaline
- Brethine or Bricanyl
- Direct selective B2 agonist
- Bronchospasm prevention
-
Fenoldopam
- Corlopam
- Direct nonselective D1 agonist
- Severe HTN
-
Dobutamine
- Dobutrex
- Direct nonselective agonist
- B1,some B2 agonist
- Refractory heart failure treatment
-
Isoproterenol
- Isuprel
- Direct nonselective
- B1,B2 agonist
- Same grouping as epi
-
Epinephrine
- Adrenalin
- Direct nonselective
- A1,A2,B1,B2 agonist
-
Norepinephrine
- Levophed
- Direct nonselective
- A1,A2,B1 agonist
-
Dantrolene
- Dantrium
- Ryanodine receptor blocker
- Stops malignant hyperthermia
-
Succinylcholine
- Anectine
- Depolarizing NM blocker
- Preop
-
Rocuronium
- Zemuron
- Non depolarizing NM blocker
- Preop
-
D-Tubocurarine
- No brand
- Nondepolarizing NM blocker
- Preop or poisen darts
-
Doxacurium
- Nuromax
- Nondepolarizing NM blocker
-
Pancuronium
- Pavulon
- Nondepolarizing NM blocker
-
Cisatracurium
- Nimbex
- Nondepolarizing NM blocker
-
Vecuronium
- Norcuron
- Nondepolarizing NM blocker
-
Mivacurium
- Mivacron
- Nondepolarizing NM blocker
-
Pipecuronium
- Arduan
- Nondepolarizing NM blocker
-
Acetazolamide
- Diamox
- Carbonic Anhydrase Inhibitor
- Oral for glaucoma
- Bad side effects
-
Blockadren
- Timolol
- Non-Selective Beta Blocker
- Treats Glaucoma by lowering aqueous humor production, and lowering IOP by about 20-30%
-
Timoptic
- Timolol
- Non-Selective Beta Blocker
- Treatment of Glaucoma by decreasing aqueous humor production, thereby lowering IOP by 20-30%
-
Betoptic S
- Betaxolol (the syllabus says Timolol, this is a typo)
- Competitive and selective B1 blocker
- Treat Glaucoma by lowering production of aqueous humor, lowers IOP by 20-30%
-
Cosopt
- Timolol + Dorzolamide
- Timolol is a nonselective Beta blocker that reduces production of aqueous humor to lower IOP by 20-30%
- Dorzolamide is a Carbonic Anhydrase Inhibitor which also lowers aqueous humor production
- This helps treat symptoms of Glaucoma
-
Combigan
- Timolol + Brimonidine
- Timolol is a nonselective beta blocker, it reduces production of aqueous humor, which lowers IOP by 20-30%
- Brimonidine is an alpha 2 agonist, which is thought to lower aqueous humor production and increase uveoscleral outflow to lower IOP by 20-35%
- Glaucoma treatment
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