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Covering/Lining Epithelium
- SKIN
- communicates w/ outside
- digestive
- respiratory
- urinary
- reproductive
- stays internal
- chest cavity
- abdominal cavity
- endothelium of heart and blood vessels
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Glandular Epithelium
- often lines in clusters deep to covering/lining epithelium
- secretes onto surfaces, ducts and into blood
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Functions of Epithelium
- protection
- secretion
- absorbtion
- filtration
- sensation
- specialized secretion
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Characteristic of Epithelium
- specialized contacts with other cell
- polarity(different ends do different things)
- avascular(no blood supply)
- regeneration(high rate of cell division)
- cellularity(lots of cells in close contact)
- little cellular material
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Basal Lamina
basement membrane
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Lamida Lucida
- glycoprotiens/fine protein filiments
- barrier
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Lamina Densa
- bundle of coarse protein fibers
- gives basal lamina strength
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Classification of ET
- SHAPE
- squamous
- cuboidal
- columnar
- LAYERING
- simple
- stratified
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Mesothelium
- lines ventral body cavities
- simple squamous
- produces erous membrane
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Endothelium
lines blood vessels
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Simple Squamous
- single layer
- flat cells
- lines air sacs, cappilaries, lymph vessels, ventral cavity covering
- diffusion SUBSTANCES PASS EASILY
- reduces friction
- absorption/secretion
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Simple Cuboidal
- single layer
- cube shaped
- large centrally located nucleous
- lines kidney tubules and ducts of glands
- absorption/secretion
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Simple Columnar
- single layer
- tall basally located nucleous
- goblet cells
- MICROVILLI
- lines intestines
- protection/absorption/secretion
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Pseudostratified Columnar
- single layer
- tall cells
- scattered nuclei
- CILLA
- goblet cells
- lines trachea and fallopian tubes
- protection/secretion
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Stratified Squamous
- many layers
- flat cells
- KERITENIZED=epidermous
- NON-KERITENIZED=vagina, epidermous,mouth
- protection
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Transitional Epithelium
- several layers
- cells change shape under pressure
- lines urinary bladder and ureters
- DISTENSIBILITY=ability to stretch
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Tight Junctions
closes spaces between cells so that substances through cells instead of around them
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Gap Junctions
allows rapid passage of small molecules/ions from one cell to the next
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Desmosomes
bind cells tightly together like velcro
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Endocrine Glands
- DUCTLESS
- secretes into blood
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Exocrine Glands
- secretes into a duct
- secretes on to a surface
- UNICELLULAR=composed of one cell(ex. goblet)
- MULTICELLULAR=composed of many cells(ex. sweat,sebaceous and salvitory glands)
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Merocrine Secretions
- release product from vesicle through exocytosis
- watery sweat
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Apocrine Secreations
- loss of cytoplasm containing secretion
- apical(free) surface of cytoplasm is shed
- thick underarm sweat
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Holocrine Secreations
- entire cell is packed with secreation then burst
- destroys cell
- sebaceous gland associated with hair
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Membrane
- is an ORGAN
- combination of epithelium and CT that covers and protects other structures and tissues
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Serous Membrane
- lines cavities with no outside openings
- reduces friction
- secretes serous fluid
- inner lining of thoracic and abdominal cavities
- covers organs of thoracic and abdominal cavities
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Mucus Membrane
- lines tubes and organs that open to outside world
- secretes mucous
- mouth, nose, throat, digestive tract ect.
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Synovial Membrane
surrounds joint cavities
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3 Components of CT
- cells
- ground substance
- fibers
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-cyte
fully differentiated
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-blast
- derived from progenitor cells
- early stages of differentiation
- active in synthesis
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Fibroblasts
- "work horses"
- fix damages(ex. scars)
- large star-shaped
- secretes proteins that become fibers
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Macrophages
- motile
- sometimes attach to fibers
- clear foreigh substances
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Mast Cells
- large
- usually near blood vessels
- release chemicals to promote inflammation
- heparin/histomine
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Collagen Fibers
- thick threadlike
- can withstand lots of tension
- holds structures together
- ex. tendons/ligaments
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Elastic Fibers
- thin and stretchy
- able to bounce back
- ex. vocal cords and air passages
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Reticular Fibers
- thin fibers of collagen
- makes a "mesh-work"
- allows cells to stay in CT
- support networks
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Ground Substance
- HYDROPHYLLIC
- controls passage of substances through matrix
- hydrate CT
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GAG's- glycosaminoglycans
- (-) charged polysaccharides
- major molecule of ground substance
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Tendons
- dense regular CT
- connects muscle to bone
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Ligaments
- dense regular CT
- bone to bone
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Aponeurosis
- dense regular CT
- broad fibrous sheets
- muscle to muscle(or bone)
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Aerolar CT Proper
- fibroblasts
- collagen and elastic fibers
- semiliquid matrix
- binds skin to underlying organs
- fills spaces between muscles
- diffusion and cushioning
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Dense Regular CT Proper
- fibroblasts
- collagen fibers
- semiliquid matrix
- located in tendons and ligaments
- attachments
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Dense Irregular CT Proper
- fibroblasts
- collagen fibers
- semiliquid matrix
- located in capsules of visceral organs, dermis, periostea, perichondria
- good for places where stress takes place in any direction
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Adipose
- adipocytes
- reticular fibers
- semiliquid matrix
- located in body fat areas
- insolation, protection and stores energy
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Reticular CT Proper
- fibroblasts
- reticular fibers
- semiliquid matrix
- located in basement membrane, spleen and liver
- supports
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Elastic CT Proper
- fibroblasts
- elastic fibers
- semiliquid matrix
- located in heart and lungs
- duribility with stretch
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Mesenchyme
- located in embryos
- gives rise to all other CT
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Hyaline Caritlage
- chondrocytes
- closely packed collagen fibers(so close you can't see them)
- semisolid matrix
- located in ribs, ends of bone and nose
- covered by dense pericardium
- dense irregular CT
- chondrocytes arise from this and secrete matrix
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Elastic Cartilage
- chondrocytes
- elastic fibers
- semisolid matrix
- located in the external ear and larynx
- maintains shape with flexiblity
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Fibrocartilage
- chondrocytes
- dense interwoven collagen fibers
- semisolid matrix
- located in intervertibral disks
- less firm but tougher then hyaline cartilage
- strength and shock absorbers
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Bone
- osteocytes
- collagen fibers
- solid matrix
- DENSE=outer bone
- SPONGY=inner bone
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Blood
- Erythrocytes
- leukocytes
- platlets
- plasma
- fibrinogen
- liquid matrix
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Fascia
- connections between organs and the rest of the body
- strength, stability, organ position and conduits
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Superficial Fascia
- subcutanious(hypodermis) layer
- aerolar tissue
- fat
- between skin and organs
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Deep Fascia
- strong fibrous framework
- dense CT
- bound to capsules, tendons and ligaments
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Subserous Fascia
- between serous membrane and deep fascia
- areolar tissue
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Fibrous Pericardium
fascia in the heart
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Muscle Contractility
- major property of ALL muscle tissue
- ability to shorten muscles forcefully
- causes movement
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Skeletal Muscle
- striated
- voluntary
- multi-nucleated
- unbranched
- canNOT divide but new fibers can form from other cells
- SATELLITE(PROGENITOR) CELLS FORM MYOBLASTS WHICH GROW INTO MUSCLE FIBERS
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Smooth Muscle
- walls of organs and blood vessels
- skin
- involuntary
- NOT striated
- single central nucleous
- unbranched
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Cardiac Muscle
- involuntary
- autorythmic
- striated
- branched
- single nucleous
- (cardiocytes, cardial myocytes, myocardial cells)
- INTERCALATED DISKS(gap junctions & desmosomes)
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Nervous Tissue
- conducts nerve impulses
- sensory reception
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Neurons
- recieve and transmit signals
- soma, dendrites, axons
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Neuroglia Cells
- maintain structure
- repairs framework
- performs phagocytosis
- provides nutrients NOT neural but "neuron support"
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Inflammation
- redness and heat due to increased blood flow
- swelling and pain due to the chemicals released
- loss of function which tells body to stop and heal
- INFLAMMATION -> REPAIR
- HOMEOSTASIS B/C OF REGENERATION
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Mast Cells
- degranulate and release heparin(keeps blood flow increases nutrients) and histamine(dialates blood vessels gets leaky)
- increases number and activity level of phagocytes
- removes toxins and waste
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Function of Integument
- protection from mechanical, chemical, bacterial damage and UV rays
- temp. regulation
- fluid conservation
- excretion
- vitamin D which helps with calcium absorption
- sensation(touch and pressure)
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Epidermal Stratum
- 1. Cornium=dead epithelium, keritenized, non-nucleated
- 2.Lucidum=NOT in thin skin, THICK SKIN ONLY
- 3. Granulosum=3-5 layers of flattened granular cells
- 4. Siposium=many layers, developing keratin
- 5. Basale=deepest, single row of cuboidal/columnar cells that divide and grow, melanocytes ATTACHED TO DERMIS BY BASEMENT MEMBRANE
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