AA and Catecholamine.txt

When is Arginine an essential AA?

Only during rapid fetal growth
What hormone stimulates PNMT?

Cortisol
What is Alpha-methyldopa use for pharmaceutically?

hypertension
How are catecholamines recycled?

Monoamine reuptake (NET, DAT)
What drug inhibits monoamine reuptake?

Cocaine
What is the role of VMAT-2?
- Uptake of catecholamines into presynaptic vesicles
- (H⁺/Catecholamine antiport)
What is the role of MAO?

degrade catecholamines into an acid if they are not taken up by their Monoamin reuptake (like NET)
What causes Parkinson's disease?
- Lack of Dopaminergic neurons
- Dopamine cannot cross BBB alone
What is the function of Ldopa and what must accompany it to work?
- It can cross the BBB
- Helps raise levels of Dopamine by activating AADC
- Carbidopa is used to inhibit AADC so Dopamine is not created and rejected

Author

kepling

44033

Card Set

AA and Catecholamine.txt

Description

AA and Catecholamine

Updated

2010-10-21T19:22:13Z

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