Lipoprotein disorders.txt

Name the two hyperlipidemias
- Type IIb - mixed VLDL/LDL
- Type III - High IDL
Name the two hypertriglyceridemias
- Type I - High CM
- Type IV - High VLDL
Name the one Hypercholesterolemia

Type IIa - High LDL
What are the two familial diseases that do not cause Xanthomata?
- Type IIa (high LDL)
- Type IV (High VLDL)
What is the one familial disease that does not cause CVD?

Type I (High CM)
What is the main cause of type IIa?

deficient LDL receptors
What causes Type I?
- Deficient Lipoprotein lipase
- Apo C-II deficiency
What causes Type IV?
- VLDL overproduction in liver
- obesity, ethanol
- IR
What causes type IIb?

overproduction of Apo B-100
What causes type III?

deficient Apo-E
What do LDLs do to macrophages?
- Turn them into foam cells b/c of the excess CE production
- Leads to atherosclerosis
What two drugs can be used to elevate HDL levels to remove cholesterol from macrophages?
- Fibrates
- Niacin

Author

kepling

43794

Card Set

Lipoprotein disorders.txt

Description

Lipoprotein Disorders

Updated

2010-10-20T21:10:00Z

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