What syndrome is caused when HGPRT is below 1% normal levels?
LN Syndrome
How does Allopurinol resolve primary gout?
Causes xanthine oxidase to convert allopurinol to an inhibitor of xanthine oxidase so hypoxanthine and xanthine can be excreted instead of converted into uric acid
How does Rasburicase help with Tumor lysis syndrome?
It is a urate oxidase that converts uric acid to soluble form
How does pegloticase help tumor lysis syndrome?
Increased half-life over rasburicase
How does febuxostat function?
non-purinol inhibitor of xanthine oxidase
more effective than allopurinol but more expensive