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Bio Lecture Ch 7.1
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signal transduction pathway
a sequence of molecular events and chemical reactions that lead to cell response to a signal.
Autocrine
signals that diffuse to and affect
the cells that make them.
EX- cancer cells on normal cells. reproducing the cells uncontrollably.
Paracrine
signals that diffuse and affect
nearby cells
.
EX- a neurotransmitter made by one nerve and diffuses to the next and stimulates it
A signal transduction pathway needs?
a signal
a receptor
a response
Protein Kinase
an enzyme
function- transfers phosphate group from ATP to another molecule (an amino acid)
Responder
the second component of a signal transduction pathway
A change in the responders is key because??
the signal outside has trasduced to a protien
the responder can act (ex-bind)
the signal is amplified (conversion of one molecule to many of another)
Steps in a typical eukaryotic signal transduction pathway
a receptor protein changes after being signaled
a change in the receptor protien activates protein kinase, causing a transfer of a phosphate group (ATP to target protein)
this transfer alters the responder protein function
the signal is amplified
a protein that bind to DNA is activated
the expression on certain genes is turned on or off
cell activity is altered
Author
Anonymous
ID
43545
Card Set
Bio Lecture Ch 7.1
Description
Chapter 7.1, What are signals and how do cells respond to them? KEY TERMS
Updated
2010-10-20T01:14:51Z
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