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Microcytosis
the presence of small red blood cells
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Macrocytosis
the presence of large red blood cells
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Anisocytosis
the presence of red blood cells of unequal size (an= without; iso= equal)
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Poikilocytosis
the presence of large, irregularly shaped red blood cells (poikil/o= irregular)
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Reticulocytosis
an increase of immature erythrocytes in the blood
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Erythropenia
an abnormally reduced number of red blood cells
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Lymphocytopenia
an abnormally reduced number of lymphocytes
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Neutropenia
a decrease in the number of neutrophils
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Pancytopenia
an abnormally reduced number of all cellular components in the blood
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Hemolysis
breakdown of the red blood cell membrane
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Immunocompromised
impaired immunological defenses caused by an immunodeficiency order or therapy with immunosupressive agents
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Immunosupression
Impaired ability to provide an immune response
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Lymphadenopathy
the presence of enlarged (diseased) lymph nodes
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Splenomegaly
enlargement of the spleen
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Acquired Immunodeficiency Syndrome (AIDS)
a syndrome caused by the human immunodeficiency virus (HIV) that renders immune cells ineffective, permitting opportunistic infections, malignancies, & neurological diseases to develop; it is transmitted sexually or through exposure to contaminated blood
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Anemia
a condition in which there is a reduction in the number of red blood cells, the amount of hemoglobin, or the volume of packed red cells within the blood, resulting in the diminished ability of the red blood cells to transport oxygen to the tissue (3 common types= aplastic anemia, iron deficiency anemia, pernicious anemia)
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Aplastic Anemia
a normocytic-normochromic type of anemia characterized by the failure of bone marrow to produce red blood cells
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Iron Deficiency Anemia
a microcytic-hypochromic type of anemia characterized by a lack of iron, affecting production of hemoglobin & characterized by small red blood cells containing low amounts of hemoglobin
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Pernicious Anemia
a macrocytic-normochromic type of anemia characterized by an inadequate supply of vitamin B12, causing red blood cells to become large, varied in shape, & reduced in number
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Autoimmune Disease
any disorder characterized by the abnormal function of the immune system that caused the body to produce antibodies against itself, resulting in tissue destruction or loss of function (rheumatoid arthritis, lupus)
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Erythroblastosis Fetalis
a disorder that results from the incompatibility of a fetus with an Rh-positive blood factor & a mother who is Rh-negative, causing red blood cell destruction in the fetus; necessitates a blood transfusion to save the fetus
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Rh Factor
the presence, or lack, of antigens on the surface of red blood cells that may cause a reaction between the blood of a mother & fetus, resulting in fetal anemia
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Hemochromatosis
a hereditary disorder that results in an excessive buildup of iron deposits in the body
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Hemophilia
a group of hereditary bleeding disorders in which there is a defect in clotting factors necessary for the coagulation of blood
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Leukemia
a chronic or acute malignant (cancerous) disease of the blood forming organs, marked by abnormal leukocytes in the blood & bone marrow; classified according to the white cells affected (myelocytic, lymphocytic, etc)
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Myelodysplasia
a disorder within the bone marrow characterized by the proliferation of abnormal stem cells (cells that give rise to different types of blood cells); usually develops into a specific type of leukemia
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Metastasis
the process by which cancer cells are spread by blood or lymph circulation to distant organs
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Mononucleosis
a condition caused by the Epstein-Barr virus characterized by an increase in mononuclear cells (monocytes & lymphocytes) in the blood, along with enlarged lymph nodes (lymphadenopathy), fatigue, & sore throat (pharyngitis)
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Polycythemia
an increase in the number of erythrocytes & hemoglobin in the blood
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Septicemia
a systemic disease caused by the infection of microorganisms & their toxins in the circulating blood
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Thrombocytopenia
a bleeding disorder characterized by an abnormal decrease in the number of platelets in the blood, which impairs the clotting process
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