-
-
- Organic
- compounds composed of only hydrogen and carbon
- - Hydrophobic (don’t like water)
- - C, H
-
-
-
-
Isomer
- same molecular formula (same # of atoms and
- same elements), but different structural formula(thus different properties)
-
Alcohols
- - Composed of C and H, but have no hydroxyl
- groups.
- -Polar.
- - C, H,O, (OH-)
-
Geometric Isomer
- same covalent partnerships, but differ in the arrangements of their double bonds.
-
-
Structural
- Differ
- in the arrangements of their atoms and may differ in the location of double
- bonds.
-
Hydroxyl
group- (---OH)or (HO---)
- Hydrogen
- atom is bonded to an oxygen atom, which bonds to the carbon skeleton of the
- organic molecule.
-
Carboxyl Functional group-
(--COOH)
- The entire group when an oxygen atom is double
- bonded to a carbon atom that is also bonded to an –OH group.
-
Phosphate Functional
group- (--OPO3)
- Phosphorus atom bonded to four oxygen atoms; one
- oxygen is bounded to the carbon skeleton; two
- oxygens carry negative charges.
-
- Consists of Nitrogen atom bonded to two hydrogen
- atoms to the carbon skeleton
-
What Functional group does this bond belong to?
Amino Acid
-
What functional group does this bond belong to?
Phosphate
-
What functional group does this bond belong to?
Hydroxyl Group
-
What functional group does this bond belong to?
Carboxyl
-
What is a functional group?
- 1)
- chemical
- groups that affect molecular function by being directly involved in chemical
- reactions.
- -hydrophilic and make compounds more hydrophilic (absorb in water)(increase
- solubility)
- The "R"
-
What Elements make up Carbohydrates?
(CH2O)
-
What elements make up alcohols?
-
What elements make up a hydrocarbon?
C,H
-
What elements make up a Lipid(fat)?
C,H,O(P,N)
-
Describe Dehydration
-
- ii.
- Use enzymes (macromolecules that speed up chemical
- reaction)
-
- iii.
- Linkage
- of small molecules to make larger molecules
-
Describe Hydrolysis
- i.
- Reverse of Dehydration
-
- ii.
- Inserts water to break a bond
-
- iv.
- Breaking
- large molecules into smaller molecules
-
What is a carbohydrate?
used as an energy source
-
What are the building blocks of a carbohydrate?
- Carbons
- hydrogens and oxygens
-
What are the building blocks of a protein?
- consists
- of carbon, hydrogen, nitrogen, oxygen, and sometimes sulfur
-
Fats
glycerol and fatty acids
-
Nueclotide Based Molecules
- 5
- carbon sugar,nitrogen base, and phosphate group (DNA, RNA)
-
Monosacharides-
(mono-single/one).
- Sugar
- , 3-7 carbons and 2 or more OH groups
- Those
- with 5 or more carbons form ring structures
-
- Formed
- by Dehydration Synthesis
- Examples:
- Sucrose (glucose and fructose), Lactose ( glucose and galactose) Maltose
- (glucose and glucose)
-
- Three or more monosaccharides
- Serve
- as storage macromolecules
- Ex.
- Starch – storage form of sugar serve as building materials
- Ex. - Cellulose- cell walls of plants
- -
- Glycogen – in animals. Form in which sugar is
- stored in certain animal tissues (liver & Muscle). Stored in small
- granules.
-
sucrose
glucose and fructose
-
lactose
glucose and glactose
-
maltose
glucose and glucose
-
What is a structural Isomer?
- Differ
- in the arrangements of their atoms and may differ in the location of double
- bonds. Same molecular, different structural formula.
-
What are 3 monosaccharide monomers?
- glucose,
- fructose, galactose
-
What are 3 disaccharide monomers?
- succross,
- lactoss, maltose
-
What are 3 examples of a pollysaccharide?
- Starch
- – storage form of sugar serve as building materials
- - Cellulose- cell walls of plants
- Glycogen – in animals. Form in which sugar is
- stored in certain animal tissues (liver & Muscle). Stored in small
- granules.
-
Describe a primary protein structure
- first)-the
- particular sequence and types of amino acids.
-
- i.
- like composing words from the alphabet
-
- ii.
- primary structure determined by the inherited
- genetic info.( not random linking!)
-
Describe a Secondary protein structure?
- )-“repeated
- pattern” or arrangement- hydrogen bonding responsible for helical patterns or sheet-like
- pat terns (Pleated sheets)
-
- i.
- Result of hydrogen
- bonds between the repeating constituents
- of the polypeptide backbone.
-
Tertiary
- (3rd)-three
- dimensional, globular or coiled, fibrous (helixes or pleated sheets may be
- parallel to eachother)
-
- i.
- Overall shape of a polypeptide resulting from
- interactions between othe sie chains of the amino acids
-
Quaternary
- 4th)-
- results from the interaction of 2 or more polypeptide chains.
-
- i.
- Overall protein structure that results from the
- aggregation of polypeptide units.
-
What are amino acids?
the building blocks of protiens?
-
what are the building blocks of amino acids
- i.
- Carboxyl and amino groups
-
What is the denaturation of proteins? and name an example
- 1)
- proteins are exposed to increased temperatures
- or chemicals. Loss of structure
- EX: egg whites before and after heat
-
what is an enzyme?
- 1)
- specialized macromolecules that speed up chemical
- reactions in cells
-
Components
of Nucleotides
- 5 Carbon Sugar- ribose and deoxyribose
- Nitrogen containing base (ring)
-
what is the function of the nucleotide based molecule, ATP(Adenosine Triphosphate)?
- High energy molecule that transforms energy
- around the cell. Nitrogen containing base, sugar and 3 phosphate groups.
-
what is the structure of ATP?
Nitrogen containing base, sugar and 3 phosphate groups.
-
-
what is DNA made up of?
Rungs(bases) and uprights (sugar and phosphate) thymine, guanine, cytosine, and adenine
-
What is RNA composed of?
the same as DNA expt instead of thymine it has uricile
-
what does NADH and FADH do?
- Transport H atoms and e- in metabolism. Roam
- around cell and pick up electrons to another
- part in cell and drop it off
-
- this reaction is also reversable. it can loose the e and go from NADH to NAD
-
WHat is the structure of NADH?
- nicotinamide
- ,adenine ,dinucleotide
-
What is the structure of FADH?
- flavin,
- adenind, dinucleotide
-
Compare and contrast DNA and RNA
-
Describe Transcription
- 1)
- DNA (storehouses of instructions to build
- proteins). Enzyme,Helicase, unwinds DNA
- so expose instructions. Another molecule copies them to form RNA.
-
Describe Translation
- The RNA goes through
- the nuclear pores (gatekeeper) and takes it the Ribosome.
- The ribosome (like a machine) builds a
- specific type of amino acids. When the chain of amino acids are finished they
- move from the ribosome into a machine that folds it into its particular shape
- for function, a protein (like hemoglobin)
-
Lipids with fatty acid components
- i.
- fatty acid: consists of a carboxyl group
- attatched to a long carbon skeleton
-
- ii.
- don’t dissolve in water, waxed and cutin
-
Lipids without fatty acid components?
- i.
- Steroids, four carbon rings, hormones
-
What is a Triglyceride and what is its function?
- One glycerol with three fatty acids produce a
- triglyceride by bonding. When they bond dehydration occurs and the waters are
- taken out.
- It’s a fat, so it stores energy for animals
- and people
-
What is the function of a Phospholipid?
Make up cell membranes
-
Describe a phospholipid
- b. Has a hydrophilic head and two hydrophobic
- tails
- c. It has two (not three like
- they fat molecule) fatty acid tails
- attached to the glycerol head.
- d. form
- bilayer in environment with water.
-
-
Testosterone and Estrogen
-
saturated fat
- has
- a straight tail because all hydrogen have single bonds.(butter)
-
unsaturated fat
- has
- a kink in the tail because of the double bond in the hydrogen (oil)
-
what is a chromosome?
- a
- cellular structure carrying genetic material that is found in the nucleus of
- eukaryotic cells. A bacterial chromosome is found in the nuecleoid region
-
gene
- unit of
- hereditary info consisting of a specific nucleotide sequence of DNA
-
genetic code
sequence of chromosomes in a base pair
-
Cell Theory
- all organisms are composed of one or more cells.
- The cell is the basic living unit
- All cells arise from pre-existing cells
-
What are the common characteristics of cells?
- plasma membrane
- cytoplasm
- genetic material
-
how do cells differ?
size and structure. (morphology and physiolgy)
-
Plasma Membrane
- phospholipids
- are major component; controls what enters and leaves the cell (homeostatic)
-
Cytoplasm
- thick
- (like syrup), made of water and ribosomes.
-
Genetic Material
- DNA
- which is found in the nucleus of eukaryotes but found in the nucleoid region of
- prokaryotes
-
Prokaryotes
*Domain- Archaea and Bacteria
*Structurally less complex
*Average 1-10 microns
*No membrane bound organelles
*Nucleoid region
*Cell division by binary fission
-
Eukaryotes
- *Domain Eukarya Kingdoms- Plantae, Anamilia, Fungi, Protista
- *Structurally more complex
- *single and multicellular organelles
- *Larger than 10-100 microns(micrometers)
- *Membrane bound organelles
- *True nucleus
- * Cell division by cytokinesis preceeded by mitosis or meiosis.
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-
Campare and contrast Prokaryotes and Eukaryotes
- Prokaryotes and Eukaryotes both have DNA, a plasma membrane, cytoplasm, and ribosomes.
- Prokaryotes have DNA in the
chromosome in nucleoid region. - Eukaryotes have DNA chromosome in the nucleus. They also have membrane bound organelles, Cytomembrane system(golgi bodies, ER, lysosomes)
-
what is the function of the Nucleus
- contains
- most of the DNA in the cell and is surrounded by a double membrane.
-
Nuclear membrane
- i.
- separates the DNA in the nucleus from the
- rest of the cell. It also stores genetic information and controls cytoplasmic
- chemical reactions.
-
Necleoplasm
- i.
- The
- fluid contained within the nucleus of a eukaryote in
- which the chromosomes and nucleoli are found.
-
Nucleoli
- Found
- in the cytoplasm of the cell. composed of proteins and nucleic acids. Used in
- formation of ribosomes
-
Chromosomes
- genetic
- info. Single piece of coiled DNA
-
Nucleopores
security gate
-
Cytoplasm
- contains
- the rest of the organelles such as ER, mitochondria, etc. Outside of the
- nucleus
-
Rough ER
- - attached to the outside of the
- membrane. It is the machine that helps with protein synthesis. It reads the
- messenger RNA to make the new protien
- Smooth ER-contains
- enzymes involved in lipid and steroid synthesis and detoxification. lacks bound
- ribosomes
-
Smooth ER
- contains
- enzymes involved in lipid and steroid synthesis and detoxification. lacks bound
- ribosomes
-
Golgi bodies
- -Its
- like the post office and each mail truck is a message being sent. It receives
- substances from the ER, then it modify’s (sorts) them and packages them and
- sends them off to the plasma membrane
-
Mitochondria
contains a Matrix, cristae, inner membrane, outer membrane, intermembrane space,
-
Matrix
- i.
- contains DNA(not found in the nucleus) and
- enzymes involved in metabolic activities. Inclosed by the inner membrane. Involved in
- cellular resperation
-
Cristae
- formed
- by the inner membrane infoldings. Divides
- mitochondrion into two separate parts.
-
Inner Membrane
- Makes
- the folding that form Cristae. Narrow region between the inner and outer membranes
-
Outer Membrane
- - includes
- proteins that can be used by the matrix to convert lipid substances.
-
Intermembrane space
- contains
- enzymes that use ATP to phosphorylate
- other nuceotides
-
what is a Plastid?
closely related plant organelles
-
Chloroplasts
- site
- of photosynthesis. Convert solar energy to chemical energy by absorbing
- sunlight.
- Has a thylakoid membrane, grana, theylakoidj space and stroma
-
THylakoid membrane
- system of interconnected membranes that are arranged
- into stacked and unstacked regions called grana and stroma thylakoids.
-
Grana
- series
- of stacked thylakoid disks containing chlorophyll; found in the inner membrane
- of chloroplasts.
-
Thylakoid space
interior of thylakoids
-
Photosynthesis
takes place in the chloroplasts
-
stroma
surrounds the thylakoid space. Contains free ribosomes and copies of the chloroplst genome
-
Chromoplasts
- i.
- synthesize and cartenoid pigments, yellow,
- orange, red, or brown, that give flowers and fruits their color.
-
Leucoplasts
- Storage
- sites and synthesis for startch
- Can
- change into chloroplasts when exposed to light
-
Vacuoles and peroxisomes
- contain
- cell sap,water, sals, sugars, protein enzymes, storage agent. Increases cell
- area.
-
Lysosomes
- digest
- materials taken into the cell
-
Hydrolytic enzymes
made by rough ER, recycle the cells own genetic material
-
Intracellular digestion
carried out by lysosomes
-
-
Cytoskeleton
- network
- of fibers extending throughout the cytoplasm. (like the highway)Responsible
- for:
-
Actin filaments
globular, highly conserved
-
Intermediate filaments
family of related proteins that share common structural and sequence features
-
Microtubules
polymers that make up facilia and fagila in a 9 to 2 ratio. ( 9 outer, 2 inner)
-
-
flagella
- sperm tail
- turn in circle like boat moter to move
-
centrosomes
microtuble organizing center. regulator of cell cycle progression
-
ribosomes
make proteins from amino acids according to instructions from genes. On rough ER and free floating in cytoplasm
-
Centrioles
- i.
- composed
- of 9 microtubules. Located in cytoplasm
- replicates for animal cell divison
-
compare and contrast the plant and animal cell
- Animal Cells: Centriole Plant Cells: Chloroplast, Cell Wall Both: Cell Membrane, Mitochondrion, ribosomes, endoplasmic
- reticulum, nuclear membrane, nucleus, nucleolus, chromosome, vacuole, Golgi
- apparatus, cytoplasm, flagellum
-
how does a light microscope work?
- 1) In
- a light microscope, visible light is passed through a specimen and then through
- glass lenses. The lenses refract the light is such a way that the image of the
- specimen is magnified as it is projected into the eye, onto photographic film
- or digital sensor, ot onto a video screen.
-
how does an electron microscope work?
- 1) In
- an electron microscope it focuses a beam of electrons through the specimen or
- onto its surface.
-
describe the structer of membranes
made up of phospholipid bilayer and proteins
-
proteins components
- organic
- compounds made of amino acids
- -
-
Glycoprotein components and function
- contain
- glycan covalently attatched to polypeptide side chains.
- - They allow certain types of cell-to-cell communication, help coordinate
- complicated cellular responses to stimuli, and activate the action of other
- types of cells.
-
what is a glycoglipid composed of and its function
- glipids
- with carbohydrate attatched
-are carbohydrate attached lipids. Their role is to provide energy and also - serve as markers for cellular recognition.
-
cholesterol
- waxes,
- steroid, metabolite. Found in cell membrane
-
whats the difference between a transmembrane and peripheral proteins
1) Transmembrane are embeded into the membrane and peripheral are loosely attatched to the outside.
-
transport protein-
hydrophilic channel that certain molecules or atomic ions use as a tunnel through the membrane
-
enzymatic protein
a protein built into the membrane may be an enzyme with its ative site exposed to substances in the adjacent solution.
-
signal transduction psirotein
A membrane protein (receptor)may have a binding site with a specific shape that fits the shape of a chemical messenger, such as a hormone. the external messenger may cause a shape change in the protein that relays the message to the inside of the cell
-
intercellular joining protein
membrane bound proteins of adjacent cells may hook together in various kinds of junctions such as gap junctions or tight junctions
-
ECM
- microfilaments
- or other elements noncovalantly bounded
- to membrane proteins, function helps maintain cell shape and stabilizes location
- of certain mem. proteins
-
micrometer
one millionth 10 -6
-
decimeter
one hundreth of a meter 10-1
-
millommeter
10-3, one thousandth
-
-
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