How does the body compensate for metabolic alkalosis?
hypoventilation - usually quite ineffective (body wants to breathe!!)
How does the body compensate for respiratory alkalosis?
kidneys excrete more HCO3-
How does the body compensate for respiratory acidosis?
kidneys retain HCO3-
How does the body compensate for metabolic acidosis?
hyperventilation
What is measured to determine the status of anion gap?
Sodium - 140
Chloride - 104
HCO3- - 24
What is a normal anion gap?
gap of 12 +/- 4
What is the only situation anion gap is useful for evaluating?
metabolic acidosis:
gain of HCL or loss of HCO3- = normal gap
gain of exogenous acid = increased gap
What are the causes of anion gap acidosis?
Methanol
Uremia
Lactate
Ethylene glycol
Paraldehyde
Aspirin
Ketoacidosis
What are the causes of non-anion gap acidosis?
TPN
renal tubular acidosis
diarrhea (pancreas needs to keep producing HCO3- to replace what is lost in order to keep the pH normal in the intestines. Eventually HCO3- levels will go down = metabolic acidosis)
What is the normal level of magnesium?
1.7-2.1 mmol/L
What is the normal level of calcium?
8.5-10.5 mmol/L
Which electrolytes are intracellular?
K+, Mg
What is the equation for calculating serum osmolality?