-
Strongest immunoglobulin
IgG
-
Immunoglobulen present at birth - 6 or 8 motnths and crosses the placenta
IgG
-
-
Immunoglobulin not present at birth
IgA
-
Immunoglobulin low at birth
IgM
-
Immunoglobulin that can have a transfusion reaction
IgM
-
Immunoglobulin used for parasitic infections and the allergic response
IgE
-
A decrease in the immune response
Immunodeficiency
-
What the immune system produces
Antibodies
-
Also known as a protein
Antibodies
-
Foreign substances that trigger the immune reponse
Antigens
-
Used for severe combined immunodeficiency disease
IVIG Intravenous Immune Globulin
-
Provides protection until humoral immunity established
IVIG
-
Used after exposure to Hep B, ITP, Kawaskai disease, aids, etc
IVIG
-
Antipyretic and or antihistamine is given prior or post infusion?
prior
-
Important to monitor what thorughout an infusion?
VS
-
Signs of hypersensitivity or reaction, do what?
Stop infusion immediatley
-
Local inflammation
S/E IVIG
-
-
-
-
hypersensitivity/anaphylactic shock
S/E IVIG
-
-
Difficulty breathing
S/E IVIG
-
Juvenile Rheumatoid Arthritis AKA
Juvenile Idiopathic Arthritis
-
Crhonic autoimmune inflammatory disease
JRA
-
-
-
Symptoms last how long in JRA
>6 weeks
-
WEhat other organs does JRA effect?
heart, lungs, liver and eyes
-
What sex is mostly effected by JRA
S/E IVIG
-
Most common complaint of JRA
Morning joint stiffness accompanied by joint swelling
-
JRA commonly affects knees and joings where else?
hands and feet
-
-
-
-
-
Child may develop a limp
JRA
-
For dx, 2 of what symptoms have to accompany the 5 weeks duration of arthritis, and age onset of less than 16 years...
- warmth
- pain on motion
- limited rom
-
tx for JRT
- NSAIDS
- Celecrex
- Corticosteroids
- Antirheumatic drugs Rheumatrex, methotrexate
-
Should you use pillows under knees in JRA
NO
-
Prior to exercise for the JRA pateint, use...
heat or warm moist packs
-
Full ROM exercises when?
when pain and inflammation subsides
-
-
Chronic inflammatory disease of unknown origin
Syestemic Lupus Erythematusos
-
Race SLE common in
- African americans
- Hispanics
- Asains
-
Sex most effected by SLE
Females
-
MMost offtend diagnosed in teenage years
SLE
-
-
-
-
Butterfly rash on face
SLE
-
-
-
-
-
Joint pain/arthritis
SLE, JRA
-
-
-
-
Tx for SLE
- Corticosteroids/prednisone
- Topical steroids
- Plaquenil (antimalarial): Skin lesions/renal and arthritic pain
- Hydrochloroquin (anti malaria): skin rashes
- NSAIDS
- Methotrexate: Immunosuppresante for acute exacerbations
-
SE of corticosteroids
monitor glucose
-
Special diet issue with antimalarials
Give with milk or meals to reduce gastric irritation
-
NSAIDS issues
GI, abdominal pain, bleeding
-
Immunosuppressants issues
monitor for infect, avoid sun, wear sunscreen and sun glasses
-
Used to prevent spread of HIV to infant in ureto
HAART
-
Infants are considered HIV positive until when
status is known
-
How long do you give HAART?
Until sero conversion
-
Screen how long for HIV
18 mo
-
Screening methods for HIV
ELISA, confirmed with a Western Blot
-
HIV destroys what
CD4 T cells
-
function of CD4 T cells
normal functionof immune system
-
CD4 + T- lymphocyte count less than
200 /mm3
-
Oral candidiasis
HIV/Aids
-
Pneumocystits carinii pneumonia (PCP)
HIV/Aids
-
-
-
Chronic diarrhea
HIV/Aids
-
Hepatosplenomegaly and lympadenopathy
HIV/Aids
-
-
Delayed motor skills and mental development
HIV/Aids
-
may develop neurological problems
HIV/Aids
-
Childhood infections occur more frequent and severe
HIV/Aids
-
-
-
-
-
Protease inhibitors for children over 2 years, preventing duplication of disease
tx AIDS
-
Cotrimoxazole
- tx AIDS
- Prophalactic wks - 1 year to recude PCP and other infections
-
leading cause of death 2-5
HIV
-
beyond 5 yo, mean life span
9-10 yo
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