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cardivascular drugs...
- HTN
- hyperlipidemia
- CHF
- angina
- MI
- cardiac arrhythmias
- peripheral vasuclar disease
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blood pressure is measured by which 2 numbers?
- systolic-max arterial pressure
- diastolic-min arterial pressure
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what is HTN?
increase in systolic/diastolic blood pressure
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what is second HTN?
has another cause
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essential HTN....
no identified cause
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what is the stepped-care approach?
prior to meds, lifestyle changes may be tried.
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what do beta blockers do?
heart beat less, dilate blood vessels resulting in lowering blood pressure!
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beta blocker drugs.
zebata, lopressor, bystolic
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what do calcium channel blockers do?
relax smooth muscle blood vessels dilate which decreases blood pressure
ex: norvasc
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what does ACE stand for?
angiotension-converting enzyme
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ACE inhibitors........
lower blood pressure differently but DO NOT cause blood vessel dilation
ex:lotensin, capoten, vasotec, monopril, zestril, accupril
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angiotension II receptor blocker drugs.....
keep from binding to and activating receptors
ex: diovan
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peripheral vasodilator drugs...
relax smooth muscle letting them dilate lowering BP
ex: apresoline and minoxidil
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*Did ya know?
ROGAINE (minoxidil) lowers BP and also is used for balding
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hyperlipidemia..........
both high cholesterol/high triglycerides in the blood.
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LDL is what?
bad cholestrol
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HDL is what..?
good cholestrol
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animal products do what to cholestrol?
increase
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non-animal products do what to triglycerides?
increase
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when cholestrol and triglycerides bind to proteins what is it called?
lipoproteins
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antihyperlipidemia drugs act to:
- increase HDL levels
- decrease LDL levels
- decrease VLDL levels
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drugs called statin drugs and are used to lower cholestrol are:
lipitor, questran, pravastatin
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drug used to lower triglycerides:
lopid
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CHF is......
heart is enlarged and is too weak to pump blood
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right sided heart failure.....
pooling of blood in venous circulation producing distended neck veins, liver enlargment, and edema in the extremities.
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left sided heart failure......
backup of blood in lungs causing pulmonary edema
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1st drug used for cardiac glycosides which heart pump slower and stronger.......
digoxin
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what is the SA node?
pacemaker of heart
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negative chronotropic effect....
release of actylcholine slows electrical conduction allowing heart to fill completely bf next contraction
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postive inotropic effect..........
cardiac glycosides increase strength contractions slowing heart to pump all blood out!
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symptoms of dig toxicity....
pulse rate below 60, confusion, restlessness, N/V, diarrhea, hallucinations, yellow-green halos around lights.
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methods to treat dig toxicity.
- decrease dosage of cardiac glycoside
- decrease frequency given
- administer an antidote-questran, digibind
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vasopressor drugs...
dobutrex and dopamine
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angina......
heart muscle isn't receiving enough oxygenated blood
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what does cellular ischemia mean?
not enough oxygen getting into the cells
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if ischemia goes untreated what can happen?
MI-heart attack
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drugs to treat angina.......
- nitrates
- beta blockers
- calcium channel blockers
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beta blocker drugs for angina.....
- decreasing heart rate which decrease need for more oxygen--decrease pain
- ex: atenolol-tenormin, metoprolol-lopressor, propranolol-inderal
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calcium channel blockers for angina............
- relax smooth muscle blood vessels decrease arterial pressure--decreases hearts need for oxygen----dilates coronary arteries
- ex: amlodipine-norvasc, diltiazem-cardizem, verapamil-calan
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drugs that can prevent 2nd heart attacks........
asipirin, inderal, tenormin, lopressor
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cardiac arrhythmias........
abnormal conduction electrical impulses in heart
i.e. bradycardia, heart block, tachycardia, atrial flutter, v-fib
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periphearal vascular disease.....
decreased blood flow to extremities, heart disease, diabetes, arteriosclerosis.
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pulmonary arterial hypertension.......
high pressure in lungs require heart-lung transplant.
ex: flolan, revatio
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hypertensive crisis.....
- life threating nature of increased blood pressure.
- ex: given iv---hyperstat
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