Biochem Test #2

Which of the following coenzymes is NOT required for the activity of the pyrivate degydrogenase activity?

A. Coenzyme A
B. Biotin
C. FAD
D. Thiamin pyrophosphate
E. NAD

Which of the following cellular conditions increases the oxidation of acetyl CoA by the Krebs cycle?

A. a low concentration of AMP
B. a high NAD/NADH ratio
C. a high ATP/ADP ratio
D. a high GTP/GDP ratio
E. a high level of NADH

Which of the following statements regarding control of glycolysis in liver is correct?

A. High levels of insulin lead to phosphorylation of PFK-2
B. the glycolytic enzyme that is most highly regulated is PFK-1
C. Fructose 2,6-bisphosphate is a negative allosteric effector of PFK-1
D. dephosphorylation of fructose-bisphosphatase-2 increases its activity
E. high levels of fructose 2,6-bisphosphate allosterically activate PFK-2

High energy reducing equivalents in the protein, carb and lipid that we eat are usually associated with the .... atoms removed from these nutrients during metabolism

A. hydrogen
B. oxygen
C. carbon
D. nitrogen
E. sulfur

In an untreated Type 1 diabetic, glucose metabolism in resting skeletal muscle cells is limited most by:

A. enzymes needed for glucose synthesis
B. transport protein needed for glucose uptake
C. transport protein causing net glucose release
D. enzymes needed for glucose oxidation

Which of the following is a single (one) metabolic reaction?

A. transport of tryptophan into cells
B. conversion of tryptophan to acetoacetate
C. anaerobic glycolysis
D. conversion of lactate to pyrivate
E. transport of glucose into cells

Which of the following are products of catabolism that are used to drive anabolism?

A. ADP and ATP
B. NADPH and ATP
C. NADPH and ADP
D. NADP+ and ATP
E. NADP- and ADP

When blood glucose levels rise after a carb-containing meal, hepatocytes take up more glucose because:

A. the activity of glucokinase increases when blood glucose levels rise
B. insulin rises and causes hepatocyte glucose transporters to move to the plasma membrane
C. glucokinase is allosterically activated by amino acids derived from proteins in a meal
D. hexokinase has a low Km and can therefore phosphorylate large amounts of glucose
E. hexokinase has a very high Vmax

In an individual facing physical danger, epinephrine acting on the liver will .... glycolysis and .... gluconeogenesis.

A. inhibit, inhibit
B. stimulate, stimulate
C. inhibit, stimulate
D. stimulate, have no effect on
E. stimulate, inhibit