MED-Dopamine

Sympathomimetic

• Naturally occuring catecholamine/neurotransmitter
• Acts on Alpha and Beta receptors (dose dependent) and dopaminergic
• Dopamine maintains bloodflowin the renal/mesenteric vascular beds
• Positive inotrope, increases cardiac output and systolic BP

• Cardiogenic shock
• Hemodynamically significant hypotension (systolic 70-100 not from hypovolemia)
• Symptomatic bradycardia

Pheochromocytoma, tachydysrhythmias, VF

• In doses higher than 20 mcg/kg/min alpha effects dominate causing severe vasoconstriction
• Monitor BP 3-5 mins
• Can be deactivated by sodium bicarbonate

• Dysrhythmias
• Palpitations
• Tachycardia
• Bradycardia
• Headaches
• Anxiety
• N/V
• Tissue sloughing from extravasation
• Dyspnea
• HTN

2-20 mcg/kg/min titrate to HR

• Dopaminergic: 2-5 mcg/kg/min
• Beta: 5-10 mcg/kg/min
• Alpha: 10-20 mcg/kg/min

800 mg in 500 mL D5W or NS = 1600 mcg/mL

400 mg in 250 mL D5W or NS = 1600 mcg/mL

Should not be used as the sole agent in hypovolemic shock. Fluid resuscitation is primary treatment