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Physiology
the study of function
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Homeostasis
integration of all the body systems to produce an organism that can maintain a stable internal environment by dynamic equilibrium
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Flexion
bending, to decrease the angle between two bones to less than 180 degrees.
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Extension
straightening, to increase the angle between two bones to 180 degrees
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Hyperextension
increasing the angle between two bones beyond 180 degrees
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Plantar Flexion
standing on the toes
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Abduction
movement away from the body of the midline
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Adduction
movement toward the body or the midline
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Pronation
moving the arm so the palm of the hand is downward or moving the whole body so the face is downward
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Supination
moving the arms so that the palm of the hand is facing upward or moving the whole body so that the face is upward
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Rotation
movement of a part around a fixed point to a maximum of 180 degrees
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Depression
to lower a part
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Elevation
to raise a part
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Protraction
moving a part outward
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Retraction
drawing a part back
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Eversion
turning the sole of the foot outward
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Inversion
turing the sole of the foot inward
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Circumduction
movement of the ends of a limb to inscribe a circle 360 degrees
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Mediastinum
space between the pleural cavities that contains the thymus, lymph vessels, esophagus, trachea, and nerves
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Midsagittal
divides the body vertically through the midline into right and left halves
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Retroperitoneal
behind the parietal peritoneum but within the abdominal wall
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Mid-Axillary line
an imaginary straight line from the mid-axillary region downward that separates the anterior and posterior chest
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Mid-Clavicular line
imaginary straight line from the mid region of the clavicle downward on the anterior chest-wall
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RUQ Right Upper Quadrant
contains liver, gall bladder, head of pancreas, part of duodenum (SI), right kidney and part of the colon
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LUQ Left Upper Quadrant
contains the spleen, tail of the pancreas, stomach, left kidney and part of the colon
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RLQ Right Lower Quadrant
appendix, ascending colon small intestine and the right ovary and fallopian tube
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LLQ Left Lower Quadrant
small intestine, descending colon, and left ovary and fallopian tube
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Frontal or Coronal
divides the body into anterior (ventral) and posterior (dorsal) at right angles to the sagittal plane
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Horizontal or Transverse
dividing the body into superior and inferior portions
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Sagittal or Parasagittal
any plane parallel to the midsagittal line vertically dividing the body into right and left portions
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Dorsiflexion
standing on the heels
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Negative Feedback
a self regulatory compensatory system
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Positive Feedback
a compensatory but not self-regulatory system, seen also in pathological conditions
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Thoracic Cavity
contains the lungs
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Ventral Cavity (Thoracic Cavity)
pleural cavities houses the lungs and great vessels
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Ventral Cavity (Abdominopelvic Cavity)
- contains organs inferior to the respiratory diaphragm but above the urogenital diaphragm
- in the abdomen
- in the pelvis
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Dorsal Cavity (Spinal Cavity)
contains the spinal cord
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Dorsal Cavity (Cranial Cavity)
contains the brain
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Pericardial Cavity
houses the heart and the pericardium
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Smooth ER
- does not participate in protein synthesis
- present in cells that produce steroid-based hormones
- also abundant in cells that are active in lipid metabolism and drug detoxification
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Chromosomes
- dense, darkly staining, nuclear body
- packaging site for ribosomes
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Neucleus
- control center of cell
- necessary for cell division and cell life
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Rough ER
its cisternae modify and store the newly fromed proteins and dispatch them to other areas of the cell
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Lysosomes
- contains digestive enzymes of many varieties
- "suicide sac" of the cell
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Intermediate Filaments
contractile elements of the cytoskeleton
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Endoplasmic Reticulum (ER)
- membranous system
- involved in intracellular transport of proteins and synthesis of membrane lipids
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Mitosis
- process during which the chromosomes are redistributed to two daughter nuclei; nuclear division
- prophase, metaphase, anaphase, telophase, and cytokinesis
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Interphase
- the longer period during which the cell grows and carries out it's usual activities
- Cell formation---Cell division
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Prophase
the first stage of mitosis, consisting of coiling of the chromosomes accompanied by migration of the two daughter centrioles toward the poles of the cell, and nuclear membrane breakdown
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Metaphase
second sage of mitosis, during which the chromosomes migrate to the central plane or equator of the spindle and align along that plane in a straight line from which the superior to the inferior region of the spindle "rosette circle"
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Anaphase
3rd stage of mitosis, meiosis I, Meiosis II, in which daughter chromosomes move toward each pole of a cell
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Telophase
The final phase of mitosis, begins when migration of chromosomes to the poles of the cell has been completed and ends with the formation of two daughter nuclei
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Cell Division
when cell produces itself by dividing
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Organelles
small cellular structures "small organs"
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Peroxisomes
site of free radical detoxification
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Cytoplasm
- stored glycogen granules, crystals, pigments, and so on.
- (cellular material surrounding the nucleus, enclosed by plasma membrane)
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Ribosomes
- attached to membrane systems or scattered in the cytoplasm
- synthesize proteins
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Centrioles
- two rod-shaped bodies near the nucleus
- direct formation of the mitotic spindle
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Golgi apparatus
- membranous system consisting of flattened sacs and vesicles
- packages proteins for export
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Chromatin
threadlike structure in the nucleus; contain genetic material DNA
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Selective Permeability
- a membrane that allows certain substances to pass while restricting the movement of others
- also called "differentially permeable membrane"
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Meiosis
nuclear division process that reduces the chromosomal number by half and results in the formation of four haploid cells, occurs in certain reproductive organs
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Function of Meiosis
used only for the production of gametes (eggs and sperm) for sexual reproduction
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The Function of Cell division, Mitosis, Cytokinesis
is to high the number of cells for growth and repair, while maintaining their genetic heritage
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Cytosol
the fluid cytoplasmic material
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Filtration
used to separate particles and fluid in suspension; occurs only across capillary walls
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Cell
structural unit of all living things
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Mitochondria
- scattered throughout the cell
- major site of ATP synthesis
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Plasma Membrane
- external boundary of cell
- regulates flow of materials into and out of the cell, site of cell signaling
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Cytokinesis
the division of the cytoplasmic mass, begins during late anaphase and continues through telophase (occurs after the cell and nucleus has divided) The division of cytoplasm
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Diffusion
is the movement of molecules form a region of higher concentration to a region of their lower concentration driving force kinetic energy
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Nuclear pores
are spanned by diaphragms, these pores permit easy passage of protein and RNA molecules
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Nucleoli
are assembly sites for ribosomal particles which are the actual protein-synthesizing "factories"
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Nuclear Envelope
the double membrane barrier of a cell nucleus
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Microvilli
slender extensions of the plasma membrane that increase it's surface area
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Crenation
- crinkling-up process is due to the fact that the 5% sodium chloride solutions is hypertonic to the cytosol of the red blood cell
- water tends to leave the cells by osmosis
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Hemolysis
- in a hypotonic solution the red blood cells "plump up" then they suddenly start to disappear
- the red blood cells burst as the water floods into them, leaving "ghosts" in their wake."
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Mitotic Spindle
acts as a scaffolding for the attachment and movement of the chromosomes during later mitotic stages
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Concentration gradient
- difference in concentration
- exits the net effect of this random molecular movement is that the molecules eventually become evenly distributed throughout the environment
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Inclusions
not part of the active metabolic machinery of the cell, stored foods, crystals, water vacuoles, and ingested foreign materials
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Microfilaments
- thin strands of the contractile protein actin
- ribbon or cordlike elements
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Microtubules
- slender tubules formed of proteins called tubulins
- aggregate and disaggregate spontaneously
- organize the cytoskeleton and direct formation of the spindle formed by the centrioles during cell division
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Cytoskeletal Elements
ramify throughout the cytoplasm, forming an internal scaffolding called the cytoskeleton that supports and moves substances within the cell
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Exocytosis
movement out of the cell
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Endocytosis
movement into the cell
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Vesicular transport
large particles and molecules are transported across the membrane
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Phagocytosis
(cell eating) parts of the plasma membrane and cytoplasm expand and flow around a relatively large or solid material and engulf it
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Pinocytosis (fluid-phase endocytosis)
the cell membrane sinks beneath the material to form a small vesicle which then pinches off into the cell interior.
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Receptor mediated Endocytosis
is exquisitely selective and is used primarily for cellular uptake or specific molecules such as cholesterol, iron, and some hormones, and for transfer of substances from one side of the cell to the other
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