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Amphipathic Molecules
both hydrophilic and hydrophobic region
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Fluid Mosic Model
Cell membrane is both fluid and made of many parts
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Davson-Danielli
proposed sandwich model in 1935, proteins on both sides of membrane but not through it
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Singer-Nicolson
proposed that proteins were dispersed over surface and embedded in 1972
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Freeze Fracture
test used to split the membrane into the two layers
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Membrane Fluidity
rapid lateral movement of lipids in membrane
- - Temperature
- - Saturated/Unsaturated Levels
- - Cholesterol - restrains fluidity when warm, maintains it when cool
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Glycolipid
connected directly to membrane
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Glycoprotein
connected to carbohydrate in protein
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Peripheral Protein
attatched to one side or the other of membrane, not embedded
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Integral Protein
transmembrane protein, embedded, reinforces shape
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Asymmetrical Orientation
distinct inside/outside faces in membrane, begins during synthesis
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Protein Functions
- Transport
- Enzymatic Activity
- Signal Transduction
- Intercellular Joining
- Cell-Cell Recognition (Carbohydrates)
- Cystskeleton/ECM Attatchment
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