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lives in intestines
Fasciolopsis buski, metagonimus yokagawa, heterophyes heterophyes
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lives in liver/bile duct
fasciola hepatica, cloriorchis sihersis
-
lives in lung
parogonimus westermani
-
lives in blood
schistosoma mansoni, haematobium, japonicum
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found in Asia & India
Fasciolopsis Buski
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Very large 75mm x 20mm
fasciolopsis buski
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adults in duodenum and jejunum, few symptoms
light infection
-
worms throughout intestines, inflammation, ulceration, abscesses
abdominal pain, malabsorption, diarrhea
BOWEL OBSTUCTION
heavy infection fasciolopsis buski
-
2nd IH is a fish
heterophyes, metagonimus yokagawai
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very small w/ ventral sucker
heterophyes, metagonimus yokagawai
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sucker surrounds genital pore
gonotyle
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gonotyle along midline
heterophyes heterophyes
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gonotyle and ventral sucker fused off center
Genitoacetabulum, metagonimus yokagawai
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adults in intestines have no symptoms unless large in #s
heterophyes and yokagawai
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eggs burrow into intestinal mucosa erode tissue, carried to ectopic sites, heart failure
heterophyes & yokagawai
-
one of the first to be identified
fasciola hepatica
-
sheep liver fluke
fasciola hepatica
-
liver rot caused by
fasciola hepatica
-
metacercaria live in watercress and other water plants
fasciola hepatica
-
bifurcated structures that end blindly in fasciola hepatica
cecae
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oral sucker draws plug of tissue into fasciola hepatica
flows blood into worm
-
enzyme secretory bodies produced to break down digested blood
cyclical transformation secretory phase
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cell absorbs nutrients in fh
absorptive phase
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Juvenile fasciola hepatica in ectopic sites
produce ulcers
-
acute fascioliasis
migration of juveniles into liver causing hepatomegaly (liver swells)
-
chronic fascioliasis
blockage of bile duct, secretion of proline leads to fibrosis
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Pipestem fibrosis
causes by fibrosis of liver
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Atrophy of liver
leads to jaundice and cirrhosis, loss of liver cell function
-
oriental liver fluke
clariorchis sinensis
-
egg is eaten by snail
clariorchis sinensis
-
block bile duct and cause
erosion of epithelial tissue
-
oriental lung fluke
paragonimus westermani
-
cercaria is microcercous (small and knoblike)
paragonimus westermani
-
2 worms to one cyst
distoma cysts
-
necrosis of lung tissue causes (PW)
chest pain, coughing, blood tinged sputum
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2mg feces on slide w/ 1 drop saline
direct wet smear
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4mg feces and formalin strained w/ saline through centrifuge
decant add formalin & ethyl acetate
centrifuge and decant
formalin-ethyl acetate sedimentation concentration technique
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Westermani eggs
in sputum and feces
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muscular contraction causes paralysis, tegumental disruption of ion channels
praziquantel effects on worm
-
fasciola hepatica treated by
triclabendazole
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swells tegument and mitochondria, microtubule inhibitor disrupts formation of cytoskeleton
triclabendazole mechanism
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infect vegetation
hepatica and buski
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infect fish
yokagawai and sinensi
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infect crayfish
westermani
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