Compatibility Testing (Crossmatch) 8.8

Compatibility testing consists of a variety of tests performed before transfusion to ensure safety of who?

________ lacks fibrin clots which can cause false agglutination

_________ may inactivate complement, some antibodies may not be detected.

samples for crossmatch should not be more than ____ hours old.

________ specimens can mast true hemolysis of antigen-anitbody complexes, reject and redraw.

for Crossmatch, patient and donor RBCs should be saline washed how many times?

for what patients should you use serum/plasma of mother and infant for initial testing?

Why do you use serum from mother for patients <4 months old?

What is the form number for the Blood request form?

What is the secion of the SF 518 that contains the blood component requested, physician's name, and diagnosis or operative procedure and date and time of drawing?

in what block of the SF 518 does the person drawing blood sign?

what three persons can sign the SF 518?

Information on specimen and SF 518 must __________.

what should be done if information on specimen and SF 518 does not agree?

these may be undetectable now due to decreasing titer or dosage?

this should be checked to confirm previous serological history.

This test uses group O human RBC to detect unexpected (alloantibodies) NON-ABO antibodes in patient serum.

if antibody is identified what should be done to verify corresponding antigen?

_________ negative donor units should only be used.

Crossmatch uses recipient ________ and donor ______.

Do not used donor units if partially ________, color is _______ or ________ or if plasma shows _________.

inadequate sealing or closure of tubings or inadequate cleaning of venipuncture site can cause what?

what is the common unsuspected bacteria seen in donor units?

units appearing contaminated must be __________ and __________.

true or false
matching of donor and recipient with respect to other blood group antigens is NOT necessary unless the recipient has additional serum antibodes.
True False

Donor units MUST lack _______ corresponding to recipient Ab.

Fresh Frozen Plasma should be compatible with patient's _____.

for what type of patients are there NO acceptable FFP alternatives?

who is the universal donor for fressh frozen plasma?

who is the universal recipient for FFP?

for what blood products are all ABO groups acceptable?

_________ donor units are to be used when patients own blood type not available.

for what blood product is there no alternative?

the major factor in determining alternate ABO group is what?

What are four indications for transfusion of Non-Group-Specific blood products?

What are alternate Rh choices for Rh positive patient?

When can Rh negative patients receive Rh positive units not producing anti-D?

What are the two patients who can be converted to Rh positive?

Switching ABO groups is a ___________ problem.

true or false
it is better to give Rh negative patients an Rh negative alternate compatible blood group becuase switching ABO groups is a temporary problem.
True False

Production of Anti-D due to giving Rh positive is a _________ problem.

what percent of D-negative persons who receive a D-positive transfusion are expected to develop anti-D.

This test detects the presence of clinically significant unexpected Abs.

what phase of crossmatch may be omitted if there is a negative Ab screen and no prior record of Abs.

true or false
Crossmatch can detect all clinically significant Abs.
True False

what is the last blood bank test done prior to patient receiving transfusion?

This detects recipient antibodies that will react with donor RBC antigens.

Crossmatch will detect _____ ABO grouping errors.

Crossmatch will detect Rh D typing errors if what?

What are two situations where crossmatch will not detect all atypical antibodies in recipient's serum?

True or false
crossmatch will not prevent recipient from forming antibodies?
True False

Crossmatch must be capable of detecting what three types of antibodies?

Computer crossmatch standards are set by who?

for computer corssmatch patient must have hhow many concordant ABO/Rh types?

true or false
to perform a computer crossmatch, current antibody screen must be nonreactive and no history of antibodies.
True False

what are the two poteniating media used for crossmatch.

What is the ratio for recipient serum and Donor RBC suspension for crossmatch.

What phase of crossmatch will detect IgG antibodies and some Rh system antibodies?

how many drops of potentiator should be added to recipient serum and donor RBC suspension for crossmatch?

check cells must have what result?

Patients with _________ antibodies may show positive reactions in all phases and temps.

if there is a positve result in crossmatch what should be done?

What are the three cold autoantibodies?

what is the most common cold autoantibody?

Cold autoantibody problem Must be solved, why?

this technique is used to eliminate the activity of anti-I.

if patient has not been recently transfused, this technique will remove the Anti-I from the serum.

Adsorbed serum should be used for what three tests?

This protein problem is commonly seen in multiple myeloma patients.

Rouleaux is not seen in what phase due to serum being washed away.

how is rouleaux formation resolved?

Albumin/LISS is stabilized with what?

This will agglutinate all RBCs suspended in albumin/LISS that has caprylate?

how is albumin agglutinating phenomenon resolved in crossmatch?

if a patient has warm autoantibodies present what other test will be positive?

Warm autoantibodies are most often directed against what antigens?

If there are not units lacking antigen to patient's antibody _________ crossmatch may be needed to determine the least incompatible unit.

in titration crossmatch what are the units of preference?

Bacterial contamination may causes a false positve because red cells carry this antigen which reacts with human sera?

Sialic acid removal by enzymes exposes this antigen in vivo or in vitro.

What are the four bacterial contaminants associated with Z-neuraminidase, which can cause T-polyagglutination?

what are two false negative results which are actually misinterpreted positive results?

no agglutination/hemolysis in any phase indicates what result in crossmatch?

what three things can cause negative reaction on check cells?

This indicates serological incompatibility between recipient and donor unit.

is alternate crossmatching procedure is to be used only in emergency.

What three things should be rechecked for donors and recipients if there is an incompatible crossmatch workup?

uncrossmatched blood should be used only in what situations?

what blood type should be used for uncrossmatched blood?

who assumes responsibility for uncrossmatched blood?

uncrossmatched blood units must be labeled _________.

true or false
uncrossmatched blood should be crossmatched after the fact
True False

What section of the SF 518 must be filled out completely with compatibility testing results?

What is the expiration time for crossmatch?

Recipient specimen and dnor sample for crossmatch should be saved for ___ days post transfusion at 1-6^oC.