The _____ lung has 3 lobes and the _____ lung has 2 lobes
Right
Left
The ____ lung has fewer lobes to make room for the heart that lies on the _____ of the body
Left
Left
O2 diffuses across the alveolar wall and enters the bloodstream, while CO2 diffuses from the blood into the aveoli
true
Gas exchange occurs between the air in the ______ and blood in the capillaries
Alveolar
____ is a film of lipoprotein that lowers the surface tension and prevents them from closing
Surfactant
______ is the small amount of air that moves in and out with each breath when we are relaxed
Tidal Volume
____ is the maximum volume of air that can be moved in plus moved out during a single breath
Vital Capacity
______ is even after deep exhalation some air remains in the lungs, this air is no longer useful for gas exchange
Residual Volume
Some of the inhaled air never reaches the lungs, but instead it fills the nasal cavities, trachea, bronchi, and bronchioles
True
_____ is located in the medulla oblongata of the brain
Respiratory center
_____ is active phase of breathing
Inspiration
diaphragm and rib muscles contract
intrapleural pressure decreases
lungs expand
air comes in
order of inspiration breathing
the respiratory center stops sending neuronal signals
diaphragm and rib cage resume normal shape and pressure
air is forced out
expiration
Gas exchange between air and blood
External Respiration
CO2 will diffuse from the blood into the alveoli of the lungs
Talking about CO2 during external respiration
O2 diffuses from the alveoli into blood
Talking about O2 during external respiration
Gas exchange between blood and tissues
Internal Respiration
O2 diffuses out of blood and into the tissues
Talking about O2 during internal repiration
CO2 diffuses from the tissues into the blood
Talking about CO2 during internal respiration
Strep throat is a bacterial infection caused by _________
Streptococcus Pyogenes
______ is an infection of the cranial sinuses
______ develops when nasal congrestion blocks tiny openings leading to the sinuses
Sinusitis
_____ is a viral or bacterial infection of the lungs where the bronchi and alveoli fill with thick fluid
Pneumonia
_____ is a chronic and incurable disorder where the aveoli are distended and their walls damaged so that surface area available for gas exchange is reduced
Emphysema
______ is a disease of the bronchi and bronchiles that is marked by wheezing, breathlessness, cough, and expectorant
Asthma
4 stages of lung cancer
1. Thickening and callusing of cells lining the airways
2. Cilia are then lost
3. A tumor forms
4. Metastasis- cells break lose and penetrate other tissues
Chewed food is called _____
bolus
_____ pushes food along the digestive tract
(a rhythmic contraction)
Peristalsis
______ begins digesting starch
Salivary amylase
Gastric juice contains the enzyme ______, as well as ______, and _____
Pepsin
HCL
Mucus
Digestive protein is known as _____
pepsin
_____ causes the stomach's acidity-- important because acidity kills most bacteria found in food
HCL
_____ doesn't digest food; breaks down connective tissue in meat and activates pepsin
HCL
Alcohol is absorbed in the stomach, but food is NOT
True
When the food leaves the stomach it is a thick, soupy liquid called ______
Chyme
_____ emulsifies fat (causes fat droplets to disperse in H2O)
Bile
_____ is neutralized in the small intestine by sodium bicarbonate
Chyme
_____ in the small intestine complete the process of food digestion
Enzymes
Functions of the small intestine
1. emulsifes fat
2. neutralizes chyme
3. enzymes digest
_____ greatly increase the surface area for absorption of nutrients
Microvilli
The large intestine functions
absorb H2O , salts, and some vitamins
stores indigestible material until elimination occurs
____ are small growths arising from the colon lining
Polyos
_____ is caused by infection (food poisoning) and nervous stimulation
Diarrhea
______ is when feces are dry and hard
Constipation
Accessory organs to the digestive system
Pancreas
Liver
Gallbladder
_____ is the largest gland in the body
Liver
____ is inflamation of the liver, occurs in many forms
Hepatitus
Hep A- sewage water
Hep B- sexual contact
Hep C- infected blood
distorys liver
Liver has amazing regenerative powers
True
Pancreatic juices contain ____ and ______
Bicarbonate
Enzymes
Bile is produced in the _____ and is stored in the ______
Liver
Gallbladder
6 types of nutrients
1. Carbohydrates
2. Proteins
3. Lipids
4. Vitamins
5. Minerals
6. H2O
The 4 functions of nutrients
1. Growth
2. Maintenance
3. Repair
4. Reproduction
_____ carries cholesterol from the liver to the cells and is thought of as "bad"
LDL
______ carries cholesterol to the liver where it is converted into bile salts and is thought of as "good"
HDL
Vitamins C, E, and A are examples of _______
Antioxidants
The functions of antioxidants
defend the body against free radicals
cellular metabolism generates unstable molecules; donates electrons to DNA
Lack of vitamin D causes _____
Rickets-bowing of legs
Lack of vitamin C causes _____
Scurvy-bleeding gums
Lack of niacin causes _____
dermatitis- dark areas on the skin
_____ is binge eating then purging
Bulimia nervosa
______ is a morbid fear of gaining weight
Anorexia
_____ is when the body weight is 20% above normal
Obesity
_____ is absolutely essential to healthly life
need at least one
Kidney
_____ moves urine within the ureters
Peristalsis
_____ helps regulate H2O and pH levels in the body
Kidneys
The bladder can hold up to ____ ml of urine
600
When the ____ are closed, urination does not take place
2 sphincters
in females the reproductive and urinary systems are not connected
true
Females' urethra is _____ cm long
4
Males' urethra is ____ cm long
20
The reproduction and urinary systems are connected
True
During the production of urine, the kindeys ____
1. excrete metabolic wastes
2. maintain normal H2O-salt balance of blood
3. maintain pH balance of the blood
4. have a hormonal function
_____ is the primary nitrogenous product of metabolism
Urea
Ammonia is very toxic to the cells
The kidneys are involved in the regulating of blood pressure
______ produce urine
Nephrons
Urine formation is divided into three steps
1. filtration
2. reabsorption
3. secretion
When Na+ ions are reabsorbed, Cl+ ions follow (water follow)
NaCl (salt) reabsorption causes H2O to move from the nephron to the blood
_____ reabsorbs H2O
ADH
_____ is the increased amount of urine (more water)
_____ is the decreased amount of urine
Diuresis
Antidiuresis
If ADH is present
more H2O reabsorbed
decreased amount to urine
True
Salt reabsorption increases blood pressure
True
_____ stimulates adrenal glad to release aldosterone
Renin
______ promotes Na+ reabsorption
Aldsterone
ANH is secreted by the heart when there is increased blood volume
ALcohol inhibits ADH secretionand causes diuresis
Caffeine is a diuretic; it decreases reasorption of Na +
Urethritis - infection of the urethra
Cystitis - bladder infection
Pyelonephritis - kidney infection
Uremia - wastes accumulate in the blood
_____ are chemical signals that affet the activity of other glands or tissues
Hermones
Know glands
Hypothalamus
Pineal gland
Pituitary gland
Thyroid gland
Parathyroid gland
Thymus gland
Adrenal gland
Pancreas
Ovary
Testis
Hormones are usually controlled in 2 ways
1. Negative feedback opposes their release
2. Antagonistic hormones oppose each others actions
_____ helps to control heartbeat, body temperature, water balance
Hypothalamus
Posterior pituitary releases ADH and oxytocin, both of which are produced in the hypothalamus
_____ stimulates the thyroid to produce thyroid hormones
TSH
______ stimulates the adrenal cortex to produce cortisol
ACTH
______ stimulates the gonads to produce gametes and sex hormones
Gonadotropic hormones
_____ cause mammary glands to develop and produce milk
PRL
_____ causes skin color changes in fish, lower levels in humans
MSH
_____ promotes skeletal and muscular growth
GH
6 hormones are produced in the pituitary gland
1. TSH (Thyroid Stimulating Hormone)
2. ACTH (Adrenocorticotropic Hormone)
3. Gonadotropic Hormones
4. PRL (Prolactin)
5. MSH (Melanocyte Stimulating Hormone)
6. GH (Growth Hormone)
The amount of growth hormone (GH) produced during childhood affects the height of an individual
True
Parathyroid glands
4 glands with in the thyroid gland
_____ causes the blood phosphate level to decrease and Ca levels in the blood to increase
Parathyroid hormone (PTH)
The antagonistic actions of ______ and ______ maintain the blood Ca level within normal range
Calcitonin (thyroid gland)
PTH (parathyroid gland)
_____ has low levels of adrenal cortex hormones
Addison disease
_____ has high levels of adrenal cortex hormones
Cushing syndrome
____ lowers blood glucose level; promotes formation of glycogen
Insulin
____ raises blood glucose level; stimulates liver to break down glycogen to glucose
Glucagon
Insulin and glucagon maintain normal levels of blood glucose
Type I diabetes
Insulin dependent; pancreas is not prducing insulin
Type II diabetes
Noninsulin dependent; pancreas produces insulin, but liver and muscle cells do not respond in the usual manner
_____ are receptors on the membrane
Peptide hormones
_____ enters the cells freely
Act slower
Last longer
Steroid hormones
____ is a foreign substance that stimulates the immune system to produce antibodies
Antigen
_____ is protein produced by the body in response to an antigen
Antibody
_____ is the ability to react to antigens so that the body remains free of disease
Immunity
_____ is a state of homeostatic imbalance
Disease
There are 4 types of nonspecific defenses
1. Barriers to Entry
2. Inflammatory Reaction
3. Natural Killer Cells
4. Protective Proteins
B Cells produce antibodies
T Cells don'd produce antibodies
B Cells characteristics
antibody-mediated immunity
produced and mature in red bone marrow
reside in spleen and lymph nodes; circulate in blood and lymph
directly recognize antigen
antibody-secreting plasma cells and memory B cells
If B cells react to "self" they will die
If they can attack a foreign cell they leave the thymus
____ have constant regions that are set and variable regions that vary
immediate allergic response and parasitic infections
IgE
T Cells characteristics
cell-mediated immunity against viruses and cancer cells
produced in bone marrow; mature in thymus
antigen must be presented by APC-MHC complex
cytotoxic T cells destroy nonself cells
helper T cells secrete cytokines that control immune response
____ immunity is dependent on the presence of memory cells
Active
Active Immunity (chicken pox)
immunization
vaccine
usually last a very long time
____ signaling molecules that regulate white blood cell formation and function
cytokines
3 activites of microbes that are useful to humans
1. Ecological contributions: nutrients cycling
2. Economic and Aesthetic contributions
3. Contributions to our health
_____ digest compounds that are otherwise indigestible
(bacteria that live in large intestine)
Coliforms
______ are microbes that cause disease
Pathogens
Virulence factors allow microbes to be pathogens by conferring abililty to:
produce a toxin
adhere to surfaces
invade organs or cells
Example of where toxins go bad:
E. coli-serious intestinal disease
Clostridium tetani-prevents relaxation of muscles, leading to suffocation
Systemic diseases are more serious than local ones
True
There are 4 modes of transmission
1. Direct contact transmission
2. Airbourne transimission
3. Vechicle transmission
4. Vector-borne transmission
A disease that occurs worldwide
Pandemic
Outside a living cell, viruses are nonliving particles
inside a host cell, viruses replicate
_____ is certain viruses can remain dormant in a cell until triggered by environmental factors
Latency
6 steps of replication
1. Attachment: spikes allow virus to bind to host cells
2. Penetration: viral DNA is released into the host cell
3. Replication: host cells make copies of viral DNA
4. Biosynthesis: viral proteins are synthesized by host cells
5. Maturation: viral proteins and DNA replicate forming new viral particles
6. Release: virus gets an envelope that consist of host PM components
Surface of the flu contains 2 antigens on its spikes
1. Neuraminidase (N antigen)
2. Hemagglutinin (H antigen)
Herpes Type I
colds and fever blisters
Herpes Type II
herpes infection of the genitals
Varicella-zoster Herpes
Causes chicken pox -then remains latent
Can reoccur as shingles-later in life
Bacteria can be single cells or arranged in clusters or chains
Most bacteria are either _____ (rods) or ______ (spheres)
Bacilli
Cocci
_______ causes a greater variety of diseases than any other bacteria
Streptococcus
_____ causes food poisoning, that grows inside intestines
Salmonella
_____ produces a toxin that is the most toxic substance on earth
Botulism
_____ is a yeast that causes the widest variety of fungal infections (yeast infections)
Candida albicans
_____ is most common H2O born diarrheal disease in the US; caused by Giardia
Giardiasis
The exchange between blood and tissues refers to which type of respiration?
Internal
The loudness of your voice is due to the ______, the degree to which the vocal cords vibrate.
Amplitude
The trachea divides into 2 _______ that lead to the lungs.
Bronchi
During external respiration, CO2 diffuses from the blood into the aveoli, while O2 diffuses from the alveoli into the blood
true
A viral or bacterial infection of the lungs where the bronchi and alveoli fill with thick fluid is called ______
Pneumonia
The microvilli of the small intestine are for ____
absorption of nutrients
Pancreatic juice contains _____
Enzymes
Bicarbonate
LDL carries cholesterol from the liver to the cells and is thought of as "bad"
true
_______ is an eating disorder in which the body weight is 20% above the normal, and contributing factors can be gentic, hormonal, metabolic, and social
Obesity
The bladder can normally hold up to _____ ml of urine
600
Sphincters at the base of the bladder must be closed in order for urination not to take place.
true
______ is the primary nitrogenous end product of metabolism
Urea
Functions of the kidneys
maintain H2O-salt balance
regulate blood pH
hormone secretion
If antidiuretic hormone (ADH) is present there is _____ amount of urine
a decreased
T cells produce antibodies
true
Which pathogens secretes a toxin that prevents muscle relaxation and suffocation, also known as tetanus
Clostridium tetani
Which of the following disease categories would affect the most people
pandemic disease
Which of the following causes food poisoning and grows in the intestines for several days prior to onset of symptoms
Salmonella
The hypothalamus regulates the internal enviroment by helping to control ______
the hearbeat
body temperature
water balance
Which of the following hormones causes the mammary gland to develop and produce milk
prolactin hormone (PRL)
______ causes blood phosphate levels to decrease and blood Ca levels to increase and is secreted from the parathyroid glands; it works antagonistically with calcitonin to homoeostatic Ca levels
Parathyroid hormone (PTH)
Low levels of adrenal hormones results in ______
Addison diease
The ______ gland produces the hormone melatonin, which is involved in the ciradian rhythms