What is Plummer-Vinson syndrome, what is it associated with?
- Esophageal webs, glossitis, iron deficiency anemia
- Esophageal cancer.
What is Tylosis?
- Only genetic predisposition to esophageal cancer
- Mutation in chromosome 17
- hyperkeratosis of palms and feet.
What is the pathology of esophageal cancers?
- Squamous cell carcinoma in upper 2/3
- Adenocarcinoma in distal 1/3.
What is the most common presenting complaint for esophageal cancer?
- Odynophagia is a poor prognostic factor.
How is esophageal cancer diagnosed?
What is the predominant pathology in pancreatic cancer, in what part of the pancreas?
- Adenocarcinoma 95%
- 2/3 in pancreatic head, rest in body and tail.
What is whipple procedure, when is it done?
- Removal of head of pancreas, antrum of stomach, gall bladder, 1st and 2nd portions of duodenum
- When there is a resectable pancreatic mass.
Out of all Colorectal cancers, what percentage had an average risk (non-hereditary/inflammatory)?
- Reason for widespread screening.
Colorectal cancer is preventable, what are four screening methods?
Sigmoidoscopy, colonoscopy/polypectomy, barium enema, fecal occult blood testing.
What are the colorectal cancer screening recommendations for people of average risk?
Colonoscopy every 10 yrs starting at age 50.
What are the four stages of Colorectal cancer?
- 1: Tumor does not penetrate full thickness of bowel wall
- 2: Tumor penetrates full thickness of bowel wall
- 3: Tumor spread to local lymph nodes
- 4: Tumor spread to other organs.
At what stage of colorectal cancer is chemotherapy recommended?
Stages 3 and 4 -- not standard for stage 2.
What is a risk factor for anal cancer, who is at higher risk?
- Anal receptive intercourse
What are some symptoms of anal cancer?
Pain, bleeding, tenesmus, feeling a mass.
What is the pathology of anal cancers?
Most are Squamous cell carcinomas.