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Bacteria VS Virus
- Bacteriafree living, living cells, DNA is their genetic information
- Virusesdependent on host ribosomes, is not a cell or living, genetic information can be either DNA or RNA
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Viral Structure (5 parts)
- Genome
- Capsid
- Envelope
- Nucleocapsid
- Viral Attachment Proteins (VAP)
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Viral Attachment Proteins
Surface structure of capsid & envelope that mediate interaction of virus with target cell
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3 Types of viral infections
- •Viruses can lyse cell (kills cell)
- •Viruses can be maintained in body without symptoms (until host is immunocompromised)
- •Viruses can transform cells
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RNA Virus Classification:
+ strand viruses
Acts as its own mRNA– Called “infectiousnucleic acids” Bind to ribosomes and begin to codefor proteins
RNA-dependent RNA Polymerase first – allows it to make complementary strand (- strand) - + strand is infectious strand
Ex: Poliovirus, common cold
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RNA Virus Classification:
- (negative) strand virus
All are enveloped viruses
Needs to make its mRNA (can’t act as its own message) - Carries its own RNA Polymerase with it
Takes longer to become active than + strand viruses - non infectious
- Ex: Rabies virus
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RNA Virus Classification:
Retrovirus
- has a single strand of RNA
- carries a reverse transcriptase with it
- stays in host genome indefinately or comes out to make viral RNA
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