Drugs Chapter 5

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a. Actylcholine (ACH)
b. Monoamines (biogenic amines)
c. amino acids
d. peptides (e.g Leu-Enkephalin)

types of neurotransmitters
1. Catecholamines
a. dopamine (DA)
b. Norepinephrine (NE)
c. Epinephrine (E)

2. Indole amine
a. serotonin = 5 hydroxytryptamine ( 5 HT)

2 types of monoamines
1. Gamma aminobutyric acid -inhibitory
2. Glutamate-excitatory
3. Aspartate - predominantly excitatory
4. Glycine mostly inhibitory

examples of amino acids
Acetylcholine

Cholinergic
dopamine

Dopaminergic
norepinephrine

noradrenergic
epinephrine

adrenergic
serotonergic

serotonin
GABA(in)ergic

(GABA)
GABA

is a universal inhibitory neurotransmitter in all parts of the brain
Peptides

are long chains of amino acids molecules attacked in a specific order
Beta-lipotropin

peptide who is secreted by the pituitary gland. It is 91 amino acids long
endorphins

beta-lipotropin 16 to 30 amino acids long
enkephalins

beta-lipotropin 5 amino acids
Dynorphin A

consits of 17 amino acids
neuromodulator
- a substance that works at the synapse and influences the normal effect of the neurotransmitter at the synapse.
- it may increase or decrease the action of the neurotransmitter or it may shorten or prolong its activity
nucleus

a collection of nerve cell bodies located inside the CNS
Ganglion

a collection of nerve cell bodies located outside if the CNS
Tract

a bundle of neurons located inside of the CNS
nerve

a bundle of neurons located outside of the CNS
Cranial = sensory input to and motor
Spinal = output from the CNS

Somatic nervous system
1. sensory component 2. motor component= autonomic nervous system

visceral nervous system

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Drugs Chapter 5

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for quiz 4

Updated

2010-10-07T17:47:27Z

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